TISLELIZUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 21:41:44 GMT 2025` Edited by `admin` on `Tue Apr 01 21:41:44 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	0KVO411B3N
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

TISLELIZUMAB

Official Name

English

BGB-A317

Preferred Name

English

BGN-1

Code

English

JHL2108

Code

English

Tislelizumab [WHO-DD]

Common Name

English

BGBA-317

Code

English

tislelizumab [INN]

Common Name

English

TISLELIZUMAB [USAN]

Common Name

English

BGBA317

Code

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) SYNTHETIC CLONE 317-4B6 HEAVY CHAIN VH FRAGMENT FUSION PROTEIN WITH HUMAN .GAMMA.4 CHAIN CLONE MUT10 EFFECTOR/CONSTANT DOMAIN FRAGMENT, DISULFIDE WITH ANTI-(HUMAN PROGRAMMED CELL DEATH PROTE

Systematic Name

English

BGN1

Code

English

JHL-2108

Code

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), HUMANIZED MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-445) (HUMANIZED VH (HOMO SAPIENS IGHV4-59*01 (88.70%) -(IGHD) -IGHJ3*01 M123>T (113)) (8.7.12) (1-118) -HOM

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

708919

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

NCI_THESAURUS

C128037

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

NCI_THESAURUS

C129822

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

FDA ORPHAN DRUG

738120

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

FDA ORPHAN DRUG

863721

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

FDA ORPHAN DRUG

709919

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

Code System Code Type Description

DRUG BANK

DB14922

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

PRIMARY

FDA UNII

0KVO411B3N

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

PRIMARY

NCI_THESAURUS

C121775

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

PRIMARY

DAILYMED

0KVO411B3N

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

PRIMARY

CAS

1858168-59-8

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

PRIMARY

INN

10553

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

PRIMARY

USAN

FG-151

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

PRIMARY

SMS_ID

100000178119

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

PRIMARY

WIKIPEDIA

Tislelizumab

Created by admin on Tue Apr 01 21:41:44 GMT 2025 , Edited by admin on Tue Apr 01 21:41:44 GMT 2025

PRIMARY

From	To
1_22	1_95
1_145	1_201
1_259	1_319
1_365	1_423
2_22	2_95
2_145	2_201
2_259	2_319
2_365	2_423
1_132	3_214
1_224	2_224
1_227	2_227
2_132	4_214
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194

Glycosylation Link Type	Site
N	1_295
N	2_295

Related Record Type Details

Tislelizumab-JSGR

SUB_CONCEPT->SUBSTANCE

Amount:


					938DNF64FO

PROGRAMMED CELL DEATH PROTEIN 1

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					0KVO411B3N

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL