U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:54:39 GMT 2023
Edited
by admin
on Sat Dec 16 13:54:39 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
0KVO411B3N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TISLELIZUMAB
USAN   INN  
Official Name English
BGN-1
Code English
JHL2108
Code English
Tislelizumab [WHO-DD]
Common Name English
BGBA-317
Code English
tislelizumab [INN]
Common Name English
TISLELIZUMAB [USAN]
Common Name English
BGBA317
Code English
IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) SYNTHETIC CLONE 317-4B6 HEAVY CHAIN VH FRAGMENT FUSION PROTEIN WITH HUMAN .GAMMA.4 CHAIN CLONE MUT10 EFFECTOR/CONSTANT DOMAIN FRAGMENT, DISULFIDE WITH ANTI-(HUMAN PROGRAMMED CELL DEATH PROTE
Systematic Name English
BGN1
Code English
JHL-2108
Code English
BGB-A317
Code English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), HUMANIZED MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-445) (HUMANIZED VH (HOMO SAPIENS IGHV4-59*01 (88.70%) -(IGHD) -IGHJ3*01 M123>T (113)) (8.7.12) (1-118) -HOM
Systematic Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 708919
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
NCI_THESAURUS C128037
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
NCI_THESAURUS C129822
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
FDA ORPHAN DRUG 738120
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
FDA ORPHAN DRUG 863721
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
FDA ORPHAN DRUG 709919
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
Code System Code Type Description
DRUG BANK
DB14922
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
PRIMARY
FDA UNII
0KVO411B3N
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
PRIMARY
NCI_THESAURUS
C121775
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
PRIMARY
CAS
1858168-59-8
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
PRIMARY
INN
10553
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
PRIMARY
USAN
FG-151
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
PRIMARY
WIKIPEDIA
Tislelizumab
Created by admin on Sat Dec 16 13:54:39 GMT 2023 , Edited by admin on Sat Dec 16 13:54:39 GMT 2023
PRIMARY
From To
1_22 1_95
1_145 1_201
1_259 1_319
1_365 1_423
2_22 2_95
2_145 2_201
2_259 2_319
2_365 2_423
1_132 3_214
1_224 2_224
1_227 2_227
2_132 4_214
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Link Type Site
N 1_295
N 2_295
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL