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Details

Stereochemistry UNKNOWN
Molecular Formula C17H14O4
Molecular Weight 282.2907
Optical Activity ( - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OXINDANAC, (-)-

SMILES

OC(=O)C1CCC2=C1C=C(O)C(=C2)C(=O)C3=CC=CC=C3

InChI

InChIKey=XMTKXTUIUKKGIL-UHFFFAOYSA-N
InChI=1S/C17H14O4/c18-15-9-13-11(6-7-12(13)17(20)21)8-14(15)16(19)10-4-2-1-3-5-10/h1-5,8-9,12,18H,6-7H2,(H,20,21)

HIDE SMILES / InChI

Molecular Formula C17H14O4
Molecular Weight 282.2907
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Oxindanac, a non-steroidal anti-inflammatory drug, and is a weak cyclooxygenase inhibitor possessed antipyretic activity. This drug is used as a veterinary inflammatory drug. In addition, oxindanac was studied in phase III clinical trials for the treatment of rheumatic disorders. However, this study was discontinued.

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Patents

Sample Use Guides

Eight male volunteers receiving frusemide 40 mg b.d. were also given either oxindanac 300 mg b.d. or placebo in two consecutive periods separated by a treatment-free period, according to a randomized cross-over study design.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:14:51 GMT 2023
Edited
by admin
on Sat Dec 16 10:14:51 GMT 2023
Record UNII
0K7U57MH88
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OXINDANAC, (-)-
Common Name English
(-)-5-BENZOYL-2,3-DIHYDRO-6-HYDROXY-1H-INDENE-1-CARBOXYLIC ACID
Common Name English
1H-INDENE-1-CARBOXYLIC ACID, 5-BENZOYL-2,3-DIHYDRO-6-HYDROXY-, (-)-
Systematic Name English
Code System Code Type Description
CAS
99910-68-6
Created by admin on Sat Dec 16 10:14:51 GMT 2023 , Edited by admin on Sat Dec 16 10:14:51 GMT 2023
PRIMARY
FDA UNII
0K7U57MH88
Created by admin on Sat Dec 16 10:14:51 GMT 2023 , Edited by admin on Sat Dec 16 10:14:51 GMT 2023
PRIMARY
Related Record Type Details
ENANTIOMER -> ENANTIOMER
RACEMATE -> ENANTIOMER