CLOSIRAMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H21ClN2
Molecular Weight	300.826
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CLOSIRAMINE

Structure Search

SMILES

CN(C)CCC1C2=C(CCC3=C1N=CC=C3)C=C(Cl)C=C2

InChI

InChIKey=BYUAWKXUYPHXSR-UHFFFAOYSA-N

InChI=1S/C18H21ClN2/c1-21(2)11-9-17-16-8-7-15(19)12-14(16)6-5-13-4-3-10-20-18(13)17/h3-4,7-8,10,12,17H,5-6,9,11H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C18H21ClN2
Molecular Weight	300.826
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/37045

Clorisamine is an antihistamine drug developed by Schering in the 1970s. The drug was evaluated in phase 1 clinical trial on healthy volunteers. The results show that in a therapeutic dose of 2 mg the drug did not have any effects which might lead to an impairment of driving ability.

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:55:34 GMT 2023` Edited by `admin` on `Sat Dec 16 16:55:34 GMT 2023`
Record UNII	00T9G32ZVH
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CLOSIRAMINE

Official Name

English

8-CHLORO-11-(2-(DIMETHYLAMINO)ETHYL)-6,11-DIHYDRO-5H-BENZO(5,6)CYCLOHEPTA(1,2-B)PYRIDINE

Systematic Name

English

closiramine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

Code System Code Type Description

CAS

47135-88-6

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

SMS_ID

100000084032

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

EPA CompTox

DTXSID40866127

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

EVMPD

SUB06770MIG

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

PUBCHEM

167456

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

INN

2754

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

FDA UNII

00T9G32ZVH

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

NCI_THESAURUS

C65345

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

ChEMBL

CHEMBL1738982

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

ECHA (EC/EINECS)

256-297-4

Created by admin on Sat Dec 16 16:55:35 GMT 2023 , Edited by admin on Sat Dec 16 16:55:35 GMT 2023

PRIMARY

Related Record Type Details


					FM4R42239G

CLOSIRAMINE, (R)-

ENANTIOMER -> RACEMATE


					0R3CE06X9W

CLOSIRAMINE ACETURATE

SALT/SOLVATE -> PARENT


					F7O2396G6G

CLOSIRAMINE, (S)-

ENANTIOMER -> RACEMATE

Related Record Type Details


					00T9G32ZVH

ACTIVE MOIETY