CLOSIRAMINE ACETURATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H21ClN2.C4H7NO3
Molecular Weight	417.929
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(=O)NCC(O)=O.CN(C)CCC1C2=C(CCC3=C1N=CC=C3)C=C(Cl)C=C2

InChI

InChIKey=OSAUSAZZRQEEES-UHFFFAOYSA-N

InChI=1S/C18H21ClN2.C4H7NO3/c1-21(2)11-9-17-16-8-7-15(19)12-14(16)6-5-13-4-3-10-20-18(13)17;1-3(6)5-2-4(7)8/h3-4,7-8,10,12,17H,5-6,9,11H2,1-2H3;2H2,1H3,(H,5,6)(H,7,8)

HIDE SMILES / InChI

Molecular Formula	C4H7NO3
Molecular Weight	117.1033
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C18H21ClN2
Molecular Weight	300.826
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/37045

Clorisamine is an antihistamine drug developed by Schering in the 1970s. The drug was evaluated in phase 1 clinical trial on healthy volunteers. The results show that in a therapeutic dose of 2 mg the drug did not have any effects which might lead to an impairment of driving ability.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:12:06 GMT 2023` Edited by `admin` on `Fri Dec 15 17:12:06 GMT 2023`
Record UNII	0R3CE06X9W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLOSIRAMINE ACETURATE

Official Name

English

CLOSIRAMINE ACETURATE [USAN]

Common Name

English

SCH-12169

Code

English

8-Chloro-11-[2-(dimethylamino)ethyl]-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine compound with N-acetylglycine (1:1)

Systematic Name

English

SCH 12169

Code

English

GLYCINE, N-ACETYL-, COMPD. WITH 8-CHLORO-6,11-DIHYDRO-N,N-DIMETHYL-5H-BENZO(5,6)CYCLOHEPTA(1,2-B)PYRIDINE-11-ETHANAMINE (1:1)

Systematic Name

English

NSC-335506

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29578