SERMORELIN ACETATE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18031173 | https://www.ncbi.nlm.nih.gov/pubmed/18046908 | https://www.ncbi.nlm.nih.gov/pubmed/2429796

Sermorelin, a 29 amino acid analog of human growth hormone-releasing hormone (GHRH), is the shortest synthetic peptide with a full biological activity of GHRH which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. Intravenous and subcutaneous sermorelin specifically stimulate growth hormone secretion from the anterior pituitary. Sermorelin binds to the growth hormone releasing hormone receptor and mimics native GRF in its ability to stimulate growth hormone secretion. Hormone responses to intravenous sermorelin appear to be a rapid and relatively specific test for the diagnosis of growth hormone deficiency.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
growth hormone deficiency 2 Sources: https://www.drugs.com/cons/geref.html	Diagnostic		Approved 8583	GEREF Approved Use Diagnosing and treating growth hormone deficiency in children Launch Date 1990

Sample Use Guides

In Vivo Use Guide

1 mcg/kg bodyweight

Route of Administration: Intravenous

Substance Class	Protein Created by `admin` on `Mon Mar 31 20:35:27 GMT 2025` Edited by `admin` on `Mon Mar 31 20:35:27 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	00IBG87IQW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GEREF

Preferred Name

English

SERMORELIN ACETATE

Official Name

English

SERMORELIN ACETATE [USAN]

Common Name

English

SERMORELIN ACETATE [ORANGE BOOK]

Common Name

English

SERMORELIN ACETATE [VANDF]

Common Name

English

Sermorelin acetate [WHO-DD]

Common Name

English

Growth hormone-releasing factor (human)-(1-29)-peptide amide, acetate (salt), hydrate

Common Name

English

SERMORELIN ACETATE [MART.]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

24687