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Details

Stereochemistry ACHIRAL
Molecular Formula C14H15N3O5S2
Molecular Weight 369.416
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACETOSULFONE

SMILES

CC(=O)NS(=O)(=O)C1=CC(N)=CC=C1S(=O)(=O)C2=CC=C(N)C=C2

InChI

InChIKey=RAMPGXSXWLFXFU-UHFFFAOYSA-N
InChI=1S/C14H15N3O5S2/c1-9(18)17-24(21,22)14-8-11(16)4-7-13(14)23(19,20)12-5-2-10(15)3-6-12/h2-8H,15-16H2,1H3,(H,17,18)

HIDE SMILES / InChI

Description

Acetosulfone (promacetin®) (sodium 4,4′-diaminodiphenylsulfone-2-acetylsulfonamide) is much less toxic sulfone than sulfoxone sodium (diasone®). Acetosulfone is an antibacterial agent. It has been used in the treatment of leprosy, has been under study in the Department of Dermatology at the University of Cincinnati College of Medicine since 1949. Acetosulfone was also used for the treatment of sarcoidosis. It was tested in the treatment of the Duhring's disease.

Approval Year

PubMed

Sample Use Guides

In Vivo Use Guide
Dermatitis herpetiformis: Daily dose of three grams for a maintenance dose
Route of Administration: Oral