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Details

Stereochemistry ACHIRAL
Molecular Formula C14H15N3O5S2
Molecular Weight 369.416
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACETOSULFONE

SMILES

CC(=O)NS(=O)(=O)C1=CC(N)=CC=C1S(=O)(=O)C2=CC=C(N)C=C2

InChI

InChIKey=RAMPGXSXWLFXFU-UHFFFAOYSA-N
InChI=1S/C14H15N3O5S2/c1-9(18)17-24(21,22)14-8-11(16)4-7-13(14)23(19,20)12-5-2-10(15)3-6-12/h2-8H,15-16H2,1H3,(H,17,18)

HIDE SMILES / InChI
Acetosulfone (promacetin®) (sodium 4,4′-diaminodiphenylsulfone-2-acetylsulfonamide) is much less toxic sulfone than sulfoxone sodium (diasone®). Acetosulfone is an antibacterial agent. It has been used in the treatment of leprosy, has been under study in the Department of Dermatology at the University of Cincinnati College of Medicine since 1949. Acetosulfone was also used for the treatment of sarcoidosis. It was tested in the treatment of the Duhring's disease.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Treatment of Duhring's herpes dermatitis with acetosulfone].
1972-10-15
Sulfone drugs in Duhring's disease; further experience.
1956-06
Patents

Sample Use Guides

Dermatitis herpetiformis: Daily dose of three grams for a maintenance dose
Route of Administration: Oral
Name Type Language
SULFADIASULFONE
WHO-DD  
Preferred Name English
ACETOSULFONE
Common Name English
ACETOSULPHONE
Common Name English
ACETAMIDE, N-((5-AMINO-2-((4-AMINOPHENYL)SULFONYL)PHENYL)SULFONYL)-
Systematic Name English
N-(6-SULFANILYLMETANILYL)ACETAMIDE
Common Name English
Sulfadiasulfone [WHO-DD]
Common Name English
SULPHADIASULPHONE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C849
Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025
Code System Code Type Description
PUBCHEM
31400
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PRIMARY
FDA UNII
ZT389542XK
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PRIMARY
EPA CompTox
DTXSID70859249
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PRIMARY
NCI_THESAURUS
C77130
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PRIMARY
SMS_ID
100000085067
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PRIMARY
ChEMBL
CHEMBL3306903
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PRIMARY
CAS
80-80-8
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PRIMARY
EVMPD
SUB04621MIG
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PRIMARY
DRUG CENTRAL
61
Created by admin on Mon Mar 31 18:44:48 GMT 2025 , Edited by admin on Mon Mar 31 18:44:48 GMT 2025
PRIMARY