PRISOTINOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H18N2O
Molecular Weight	194.2734
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PRISOTINOL

Structure Search

SMILES

CC(C)NC(C)CC1=CC=C(O)C=N1

InChI

InChIKey=WQRPBKUCJBWQRT-UHFFFAOYSA-N

InChI=1S/C11H18N2O/c1-8(2)13-9(3)6-10-4-5-11(14)7-12-10/h4-5,7-9,13-14H,6H2,1-3H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1820879 | https://www.ncbi.nlm.nih.gov/pubmed/8410411

Prisotinol is aminoalkyl-5-pyridinol patented by Ciba-Geigy A.-G. for treatment of angina pectoris. Prisotinol was studied in phase II clinical trials as a cardioprotective agent.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Urinary excretion of CGS 5,649 and its conjugated glucuronide and sulfate in man.	1991	1820879

Patents

Patents

Sample Use Guides

In Vivo Use Guide

90, 200, or 600 mg

Route of Administration: Oral

Name

Type

Language

PRISOTINOL

Official Name

English

2-(2-ISOPROPYLAMINOPROPYL)-5-PYRIDINOL

Preferred Name

English

prisotinol [INN]

Common Name

English

(±)-6-(2-(ISOPROPYLAMINO)PROPYL)-3-PYRIDINOL

Systematic Name

English

3-PYRIDINOL, 6-(2-((1-METHYLETHYL)AMINO)PROPYL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C78322

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

Code System Code Type Description

INN

6606

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

PRIMARY

EPA CompTox

DTXSID10868496

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

PRIMARY

CAS

78997-40-7

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

SUPERSEDED

EVMPD

SUB10049MIG

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

PRIMARY

PUBCHEM

131302

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

PRIMARY

FDA UNII

ZPO6B92P5Y

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

PRIMARY

CAS

76906-79-1

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

PRIMARY

SMS_ID

100000081089

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

PRIMARY

ChEMBL

CHEMBL2106875

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

PRIMARY

NCI_THESAURUS

C74230

Created by admin on Mon Mar 31 18:09:48 GMT 2025 , Edited by admin on Mon Mar 31 18:09:48 GMT 2025

PRIMARY

ACTIVE MOIETY


					ZPO6B92P5Y

SALT/SOLVATE (PARENT)


					PPP3N7B22F

PRISOTINOL DIHYDROCHLORIDE