U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C18H26N2O3S.ClH
Molecular Weight 386.937
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DELEQUAMINE HYDROCHLORIDE

SMILES

Cl.[H][C@]12CCCN([C@@]1([H])C[C@]3([H])N(CCC4=C3C=CC(OC)=C4)C2)S(C)(=O)=O

InChI

InChIKey=ITJOISLXCMAIOC-CVLULELNSA-N
InChI=1S/C18H26N2O3S.ClH/c1-23-15-5-6-16-13(10-15)7-9-19-12-14-4-3-8-20(24(2,21)22)17(14)11-18(16)19;/h5-6,10,14,17-18H,3-4,7-9,11-12H2,1-2H3;1H/t14-,17+,18+;/m1./s1

HIDE SMILES / InChI
Delequamine is a selective antagonist of alpha2 adrenoreceptor, developed by Syntex Research. The compound was investigated for the treatment of erectile dysfunction and was modestly effective in younger (less than 45 years) subjects.

Approval Year

PubMed

PubMed

TitleDatePubMed
The alpha 2-adrenoceptor antagonist idazoxan reverses catalepsy induced by haloperidol in rats independent of striatal dopamine release: role of serotonergic mechanisms.
2003 May
Patents

Patents

Name Type Language
DELEQUAMINE HYDROCHLORIDE
USAN   WHO-DD  
USAN  
Official Name English
DELEQUAMINE HCL
Common Name English
Delequamine hydrochloride [WHO-DD]
Common Name English
RS-15385-197
Code English
(8aR,12aS,13aS)-5,8,8a,9,10,11,12,12a,13,13a-Decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino[2,1-g][1,6]naphthyridine monohydrochloride
Common Name English
6H-ISOQUINO(2,1-G)(1,6)NAPHTHYRIDINE, 5,8,8A,9,10,11,12,12A,13,13A-DECAHYDRO-3-METHOXY-12-(METHYLSULFONYL)-, MONOHYDROCHLORIDE, (8AR-(8A.ALPHA.,12A.ALPHA.,13A.ALPHA.))-
Common Name English
DELEQUAMINE HYDROCHLORIDE [USAN]
Common Name English
Code System Code Type Description
PUBCHEM
168898
Created by admin on Fri Dec 15 17:20:16 GMT 2023 , Edited by admin on Fri Dec 15 17:20:16 GMT 2023
PRIMARY
ChEMBL
CHEMBL163911
Created by admin on Fri Dec 15 17:20:16 GMT 2023 , Edited by admin on Fri Dec 15 17:20:16 GMT 2023
PRIMARY
CAS
119942-75-5
Created by admin on Fri Dec 15 17:20:16 GMT 2023 , Edited by admin on Fri Dec 15 17:20:16 GMT 2023
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FDA UNII
YV5E1TYM8Y
Created by admin on Fri Dec 15 17:20:16 GMT 2023 , Edited by admin on Fri Dec 15 17:20:16 GMT 2023
PRIMARY
EPA CompTox
DTXSID40923148
Created by admin on Fri Dec 15 17:20:16 GMT 2023 , Edited by admin on Fri Dec 15 17:20:16 GMT 2023
PRIMARY
MESH
C060956
Created by admin on Fri Dec 15 17:20:16 GMT 2023 , Edited by admin on Fri Dec 15 17:20:16 GMT 2023
PRIMARY
NCI_THESAURUS
C169882
Created by admin on Fri Dec 15 17:20:16 GMT 2023 , Edited by admin on Fri Dec 15 17:20:16 GMT 2023
PRIMARY
USAN
EE-72
Created by admin on Fri Dec 15 17:20:16 GMT 2023 , Edited by admin on Fri Dec 15 17:20:16 GMT 2023
PRIMARY