U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Name Type Language
Lefelsiran Sodium
USAN  
Official Name English
all-P-ambo-(3'→5')-2'-O-methyl-P-thioguanylyl-(3'→5')-2'-O-methyl-P-thioguanylyl-(3'→5')-2'-O-methyl-P-thiocytidylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5'
Common Name English
DCR-A1203
Code English
LEFELSIRAN SODIUM [USAN]
Common Name English
RNA, ([4′-de(hydroxymethyl)-4′-[(hydroxymethoxyphosphinyl)methoxy]]Um-sp-(2′-deoxy-2′-fluoro)A-sp-(2′-deoxy-2′-fluoro)A-sp-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)G-Am-Gm-Um-Um-Um-Cm-(2′-deoxy-2′-flu
Common Name English
DCR-1203
Code English
Code System Code Type Description
CAS
2728713-54-8
Created by admin on Sat Dec 16 18:30:30 GMT 2023 , Edited by admin on Sat Dec 16 18:30:30 GMT 2023
PRIMARY
USAN
KL-224
Created by admin on Sat Dec 16 18:30:30 GMT 2023 , Edited by admin on Sat Dec 16 18:30:30 GMT 2023
PRIMARY
FDA UNII
YU6F4W95PG
Created by admin on Sat Dec 16 18:30:30 GMT 2023 , Edited by admin on Sat Dec 16 18:30:30 GMT 2023
PRIMARY
Sugar Site Range Site Count
2'-O-Methyl-Ribose 1_1-1_7;1_12-1_36;2_1;2_6;2_8-2_13;2_15-2_22 48 / 58
2'-Fluoro-Ribose 1_8-1_11;2_2-2_5;2_7;2_14 10 / 58
Linkage Site Range Site Count
Sodium Phosporothioate 1_2;2_2-2_4;2_21-2_22 6 / 56
1_3-1_36;2_5-2_20 50 / 56