Details
Stereochemistry | ACHIRAL |
Molecular Formula | C21H18NO4.Cl |
Molecular Weight | 383.825 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Cl-].COC1=C(OC)C=C2C(=C1)C=[N+](C)C3=C2C=CC4=C3C=C5OCOC5=C4
InChI
InChIKey=QLDAACVSUMUMOR-UHFFFAOYSA-M
InChI=1S/C21H18NO4.ClH/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22;/h4-10H,11H2,1-3H3;1H/q+1;/p-1
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL2094255 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30132517 |
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Target ID: CHEMBL1781 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30132517 |
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Target ID: CHEMBL1843 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24794108 |
1.34 mM [IC50] |
PubMed
Title | Date | PubMed |
---|---|---|
Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. | 1991 Jan-Feb |
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HIV-1 and HIV-2 reverse transcriptases: a comparative study of sensitivity to inhibition by selected natural products. | 1992 May 29 |
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Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells. | 1999 Dec |
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Biological activities of nitidine, a potential anti-malarial lead compound. | 2012 Mar 9 |
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13063-04-2
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DTXSID50926842
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146397
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XO8WQL69T8
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25659
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admin on Sat Dec 16 07:53:52 GMT 2023 , Edited by admin on Sat Dec 16 07:53:52 GMT 2023
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PARENT (SALT/SOLVATE)
SUBSTANCE RECORD