MONOSTEARYL FUMARATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H40O4
Molecular Weight	368.5506
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCCCCOC(=O)\C=C\C(O)=O

InChI

InChIKey=MHQJUHSHQGQVTM-VHEBQXMUSA-N

InChI=1S/C22H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-26-22(25)19-18-21(23)24/h18-19H,2-17,20H2,1H3,(H,23,24)/b19-18+

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30714850 | https://www.ncbi.nlm.nih.gov/pubmed/29432807 | https://www.ncbi.nlm.nih.gov/pubmed/18396020 | https://www.ncbi.nlm.nih.gov/pubmed/3735097 | http://www.thegoodscentscompany.com/data/rw1611261.html

Monostearyl fumarate (sodium stearyl fumarate) is a lubricant for use in tablet formulation, it can be used as a taste-masking agent in orally disintegrating tablets. It is a conditioning and stabilizing agent.

Approval Year

PubMed

Title	Date	PubMed
Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution.	1986 Jun	3735097
Systematic evaluation of common lubricants for optimal use in tablet formulation.	2018 May 30	29432807

Patents

Name

Type

Language

MONOSTEARYL FUMARATE

Systematic Name

English

2-BUTENEDIOIC ACID (2E)-, MONOOCTADECYL ESTER

Common Name

English

OCTADECYL HYDROGEN FUMARATE

Systematic Name

English

FUMARIC ACID, OCTADECYL ESTER

Common Name

English

FUMARIC ACID, MONOOCTADECYL ESTER

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID20169764