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Details

Stereochemistry ACHIRAL
Molecular Formula C22H40O4
Molecular Weight 368.5506
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of MONOSTEARYL FUMARATE

SMILES

CCCCCCCCCCCCCCCCCCOC(=O)\C=C\C(O)=O

InChI

InChIKey=MHQJUHSHQGQVTM-VHEBQXMUSA-N
InChI=1S/C22H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-26-22(25)19-18-21(23)24/h18-19H,2-17,20H2,1H3,(H,23,24)/b19-18+

HIDE SMILES / InChI
Monostearyl fumarate (sodium stearyl fumarate) is a lubricant for use in tablet formulation, it can be used as a taste-masking agent in orally disintegrating tablets. It is a conditioning and stabilizing agent.

Approval Year

PubMed

PubMed

TitleDatePubMed
Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution.
1986 Jun
Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol.
2008 Aug
Systematic evaluation of common lubricants for optimal use in tablet formulation.
2018 May 30
Patents

Patents

Name Type Language
MONOSTEARYL FUMARATE
Systematic Name English
2-BUTENEDIOIC ACID (2E)-, MONOOCTADECYL ESTER
Common Name English
OCTADECYL HYDROGEN FUMARATE
Systematic Name English
FUMARIC ACID, OCTADECYL ESTER
Common Name English
FUMARIC ACID, MONOOCTADECYL ESTER
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID20169764
Created by admin on Fri Dec 15 21:31:14 GMT 2023 , Edited by admin on Fri Dec 15 21:31:14 GMT 2023
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DAILYMED
X127TT7PK9
Created by admin on Fri Dec 15 21:31:14 GMT 2023 , Edited by admin on Fri Dec 15 21:31:14 GMT 2023
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CAS
1741-93-1
Created by admin on Fri Dec 15 21:31:14 GMT 2023 , Edited by admin on Fri Dec 15 21:31:14 GMT 2023
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FDA UNII
X127TT7PK9
Created by admin on Fri Dec 15 21:31:14 GMT 2023 , Edited by admin on Fri Dec 15 21:31:14 GMT 2023
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PUBCHEM
6435831
Created by admin on Fri Dec 15 21:31:14 GMT 2023 , Edited by admin on Fri Dec 15 21:31:14 GMT 2023
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