TERBUFIBROL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C20H24O5
Molecular Weight	344.4016
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TERBUFIBROL

Structure Search

SMILES

CC(C)(C)C1=CC=C(OCC(O)COC2=CC=C(C=C2)C(O)=O)C=C1

InChI

InChIKey=PXODZCMXOZRVEN-UHFFFAOYSA-N

InChI=1S/C20H24O5/c1-20(2,3)15-6-10-18(11-7-15)25-13-16(21)12-24-17-8-4-14(5-9-17)19(22)23/h4-11,16,21H,12-13H2,1-3H3,(H,22,23)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7201785

Terbufibrol, an antihyperlipoproteinemic agent that blocks the hepatic cholesterol synthesis in a step between acetate and HMG-CoA (3-hydroxy-3-methylglutaryl-CoA). Information about the current use of this compound is not available.

Approval Year

PubMed

PubMed

Title	Date	PubMed
The hypocholesterolemic effect of terbufibrol and other drugs in normal and hypercholesterolemic baboons.	1979 Apr	223594

Patents

Patents

Name

Type

Language

TERBUFIBROL

Official Name

English

P-(3-(P-TERT-BUTYLPHENOXY)-2-HYDROXYPROPOXY)BENZOIC ACID

Common Name

English

(±)-P-(3-(P-TERT-BUTYLPHENOXY)-2-HYDROXYPROPOXY)BENZOIC ACID

Common Name

English

terbufibrol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29703

Created by admin on Fri Dec 15 15:34:33 GMT 2023 , Edited by admin on Fri Dec 15 15:34:33 GMT 2023

Code System Code Type Description

PUBCHEM

41907

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NCI_THESAURUS

C91031

Created by admin on Fri Dec 15 15:34:33 GMT 2023 , Edited by admin on Fri Dec 15 15:34:33 GMT 2023

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MESH

C020508

Created by admin on Fri Dec 15 15:34:33 GMT 2023 , Edited by admin on Fri Dec 15 15:34:33 GMT 2023

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SMS_ID

100000082704

Created by admin on Fri Dec 15 15:34:33 GMT 2023 , Edited by admin on Fri Dec 15 15:34:33 GMT 2023

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EPA CompTox

DTXSID60866568

Created by admin on Fri Dec 15 15:34:33 GMT 2023 , Edited by admin on Fri Dec 15 15:34:33 GMT 2023

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ChEMBL

CHEMBL2107542

Created by admin on Fri Dec 15 15:34:33 GMT 2023 , Edited by admin on Fri Dec 15 15:34:33 GMT 2023

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FDA UNII

W41Z308IA3

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CAS

56488-59-6

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EVMPD

SUB10912MIG

Created by admin on Fri Dec 15 15:34:33 GMT 2023 , Edited by admin on Fri Dec 15 15:34:33 GMT 2023

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INN

3961

Created by admin on Fri Dec 15 15:34:33 GMT 2023 , Edited by admin on Fri Dec 15 15:34:33 GMT 2023

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ACTIVE MOIETY


					W41Z308IA3