TERBUFIBROL

Details

Stereochemistry	RACEMIC
Molecular Formula	C20H24O5
Molecular Weight	344.4016
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)C1=CC=C(OCC(O)COC2=CC=C(C=C2)C(O)=O)C=C1

InChI

InChIKey=PXODZCMXOZRVEN-UHFFFAOYSA-N

InChI=1S/C20H24O5/c1-20(2,3)15-6-10-18(11-7-15)25-13-16(21)12-24-17-8-4-14(5-9-17)19(22)23/h4-11,16,21H,12-13H2,1-3H3,(H,22,23)

HIDE SMILES / InChI

Molecular Formula	C20H24O5
Molecular Weight	344.4016
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7201785

Terbufibrol, an antihyperlipoproteinemic agent that blocks the hepatic cholesterol synthesis in a step between acetate and HMG-CoA (3-hydroxy-3-methylglutaryl-CoA). Information about the current use of this compound is not available.

Approval Year

PubMed

Title	Date	PubMed
Mode of action of terbufibrol (INN) a hypolipidemic agent on rat liver sterol synthesis.	1982	7201785
The hypocholesterolemic effect of terbufibrol and other drugs in normal and hypercholesterolemic baboons.	1979-04	223594

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:01:40 GMT 2025` Edited by `admin` on `Mon Mar 31 18:01:40 GMT 2025`
Record UNII	W41Z308IA3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TERBUFIBROL

Official Name

English

(±)-P-(3-(P-TERT-BUTYLPHENOXY)-2-HYDROXYPROPOXY)BENZOIC ACID

Preferred Name

English

P-(3-(P-TERT-BUTYLPHENOXY)-2-HYDROXYPROPOXY)BENZOIC ACID

Common Name

English

terbufibrol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29703