TERBUFIBROL

Details

Stereochemistry	RACEMIC
Molecular Formula	C20H24O5
Molecular Weight	344.4016
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)C1=CC=C(OCC(O)COC2=CC=C(C=C2)C(O)=O)C=C1

InChI

InChIKey=PXODZCMXOZRVEN-UHFFFAOYSA-N

InChI=1S/C20H24O5/c1-20(2,3)15-6-10-18(11-7-15)25-13-16(21)12-24-17-8-4-14(5-9-17)19(22)23/h4-11,16,21H,12-13H2,1-3H3,(H,22,23)

HIDE SMILES / InChI

Molecular Formula	C20H24O5
Molecular Weight	344.4016
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7201785

Terbufibrol, an antihyperlipoproteinemic agent that blocks the hepatic cholesterol synthesis in a step between acetate and HMG-CoA (3-hydroxy-3-methylglutaryl-CoA). Information about the current use of this compound is not available.

Approval Year

PubMed

Title	Date	PubMed
The hypocholesterolemic effect of terbufibrol and other drugs in normal and hypercholesterolemic baboons.	1979 Apr	223594

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:34:33 GMT 2023` Edited by `admin` on `Fri Dec 15 15:34:33 GMT 2023`
Record UNII	W41Z308IA3
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TERBUFIBROL

Official Name

English

P-(3-(P-TERT-BUTYLPHENOXY)-2-HYDROXYPROPOXY)BENZOIC ACID

Common Name

English

(±)-P-(3-(P-TERT-BUTYLPHENOXY)-2-HYDROXYPROPOXY)BENZOIC ACID

Common Name

English

terbufibrol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29703