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Details

Stereochemistry ACHIRAL
Molecular Formula ClHO4
Molecular Weight 100.459
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PERCHLORIC ACID

SMILES

OCl(=O)(=O)=O

InChI

InChIKey=VLTRZXGMWDSKGL-UHFFFAOYSA-N
InChI=1S/ClHO4/c2-1(3,4)5/h(H,2,3,4,5)

HIDE SMILES / InChI
Perchloric acid is a strong acid used for complete digestions of organic material. To prevent injury, goggles or face shield, gloves, and apron must be worn. Perchloric acid must not be mixed with any other waste and should be stored separately from the other chemicals.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
PERCHLORACAP

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Perchloric acid in the cytochemistry of pentose nucleic acid.
1949 Nov 4
Loss of ATP in micromolar amounts after perchloric acid treatment.
1976 Nov 5
Purification and characterization of (per)chlorate reductase from the chlorate-respiring strain GR-1.
1999 Nov
Cell necrosis and apoptosis are differentially regulated during goitre development and iodine-induced involution.
2002 Feb
Functional activity of human sodium/iodide symporter in tumor cell lines.
2003 Feb
Probasin promoter (ARR(2)PB)-driven, prostate-specific expression of the human sodium iodide symporter (h-NIS) for targeted radioiodine therapy of prostate cancer.
2003 Nov 15
Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains.
2004 Apr 13
Establishment of a human hepatocellular carcinoma cell line highly expressing sodium iodide symporter for radionuclide gene therapy.
2004 Sep
A novel therapeutic strategy for medullary thyroid cancer based on radioiodine therapy following tissue-specific sodium iodide symporter gene expression.
2005 Aug
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.
2005 Feb 1
The BeWo choriocarcinoma cell line as a model of iodide transport by placenta.
2005 May
Development of a rat dosimetry model for bromate.
2006 Apr 17
Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors.
2006 Jan 5
Effects of prolonged exposure to perchlorate on thyroid and reproductive function in zebrafish.
2007 Apr
Cell-based imaging of sodium iodide symporter activity with the yellow fluorescent protein variant YFP-H148Q/I152L.
2007 Feb
Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.
2007 Mar
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 1. Effects on the brain.
2007 May 31
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 2. Effects on the tail and hindlimb.
2007 May 31
Perchlorate and ethylenethiourea induce different histological and molecular alterations in a non-mammalian vertebrate model of thyroid goitrogenesis.
2009 Jan 27
Thyroid hormone may regulate mRNA abundance in liver by acting on microRNAs.
2010 Aug 13
Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L.
2010 Mar 15
Inhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate.
2010 Nov
Goitrogenic anions, thyroid-stimulating hormone, and thyroid hormone in infants.
2010 Sep
The effects of perchlorate on thyroidal gene expression are different from the effects of iodide deficiency.
2011
The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat.
2012 Aug
Patents
Name Type Language
PERCHLORIC ACID
HSDB   MI  
Systematic Name English
PERCHLORIC ACID (HCLO4)
Common Name English
PERCHLORIC ACID [MI]
Common Name English
PERCHLORIC ACID [HSDB]
Common Name English
Code System Code Type Description
MERCK INDEX
m8537
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY Merck Index
CAS
7601-90-3
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
HSDB
1140
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
SMS_ID
100000141410
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
EPA CompTox
DTXSID8047004
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
ECHA (EC/EINECS)
231-512-4
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
CHEBI
29221
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
WIKIPEDIA
PERCHLORIC ACID
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
EVMPD
SUB91696
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
PUBCHEM
24247
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
FDA UNII
V561V90BG2
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY
MESH
D010472
Created by admin on Fri Dec 15 18:48:42 GMT 2023 , Edited by admin on Fri Dec 15 18:48:42 GMT 2023
PRIMARY