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Details

Stereochemistry ACHIRAL
Molecular Formula ClO4.Na.H2O
Molecular Weight 140.456
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM PERCHLORATE MONOHYDRATE

SMILES

O.[Na+].[O-]Cl(=O)(=O)=O

InChI

InChIKey=IXGNPUSUVRTQGW-UHFFFAOYSA-M
InChI=1S/ClHO4.Na.H2O/c2-1(3,4)5;;/h(H,2,3,4,5);;1H2/q;+1;/p-1

HIDE SMILES / InChI
Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula ClHO4
Molecular Weight 100.459
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Perchloric acid is a strong acid used for complete digestions of organic material. To prevent injury, goggles or face shield, gloves, and apron must be worn. Perchloric acid must not be mixed with any other waste and should be stored separately from the other chemicals.

Approval Year

1974
167
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8583
PERCHLORACAP

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Development of an enzymatic assay to measure lactate in perchloric acid-precipitated cerebrospinal fluid.
2018-08
The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat.
2012-08
Biomarker expression in lung of rabbit with pulmonary fibrosis induced by ammonium perchlorate.
2011-04
The effects of perchlorate on thyroidal gene expression are different from the effects of iodide deficiency.
2011
Inhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate.
2010-11
Goitrogenic anions, thyroid-stimulating hormone, and thyroid hormone in infants.
2010-09
Thyroid hormone may regulate mRNA abundance in liver by acting on microRNAs.
2010-08-13
Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L.
2010-03-15
Perchlorate and ethylenethiourea induce different histological and molecular alterations in a non-mammalian vertebrate model of thyroid goitrogenesis.
2009-01-27
Low-dose effects of ammonium perchlorate on the hypothalamic-pituitary-thyroid axis of adult male rats pretreated with PCB126.
2007-06
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 1. Effects on the brain.
2007-05-31
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 2. Effects on the tail and hindlimb.
2007-05-31
Effects of prolonged exposure to perchlorate on thyroid and reproductive function in zebrafish.
2007-04
Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.
2007-03
Cell-based imaging of sodium iodide symporter activity with the yellow fluorescent protein variant YFP-H148Q/I152L.
2007-02
[Expressions of collagen in lung of rats exposed to ammonium perchlorate].
2007-02
Development of a rat dosimetry model for bromate.
2006-04-17
Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors.
2006-01-05
A novel therapeutic strategy for medullary thyroid cancer based on radioiodine therapy following tissue-specific sodium iodide symporter gene expression.
2005-08
The BeWo choriocarcinoma cell line as a model of iodide transport by placenta.
2005-05
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.
2005-02-01
Establishment of a human hepatocellular carcinoma cell line highly expressing sodium iodide symporter for radionuclide gene therapy.
2004-09
Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains.
2004-04-13
Probasin promoter (ARR(2)PB)-driven, prostate-specific expression of the human sodium iodide symporter (h-NIS) for targeted radioiodine therapy of prostate cancer.
2003-11-15
Functional activity of human sodium/iodide symporter in tumor cell lines.
2003-02
The pharmacokinetics of perchlorate and its effect on the hypothalamus-pituitary-thyroid axis in the male rat.
2002-07-15
Cell necrosis and apoptosis are differentially regulated during goitre development and iodine-induced involution.
2002-02
Purification and characterization of (per)chlorate reductase from the chlorate-respiring strain GR-1.
1999-11
Loss of ATP in micromolar amounts after perchloric acid treatment.
1976-11-05
Application of perchloric acid technique to protozoa.
1949-12-16
Perchloric acid in the cytochemistry of pentose nucleic acid.
1949-11-04
Patents

Patents

03950331
15
03975412
6
03977981
6
04031088
19
04051260
13
04162913
17
04201879
6
04475992
6
04495357
6
04518774
6
04519938
6
04532355
7
04596809
7
04656310
7
04663260
6
04833209
6
04954518
13
04990517
10
05110945
10
05145893
9
05191108
9
05200518
8
05220042
7
05663364
6
05670650
6
05770605
7
05981580
6
05998463
8
07022716
9
07132416
6
07153873
7
07163951
8
07169407
10
07273857
11
07300928
11
07429660
7
07626021
11
07662861
6
07829558
6
08030501
6
08124783
8
08304544
8
08785638
6
08791108
6
08835632
6
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:20:12 GMT 2025
Edited
by admin
on Mon Mar 31 20:20:12 GMT 2025
Record UNII
G4H485LHCW
Record Status Validated (UNII)
Record Version
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Name Type Language
SODIUM PERCHLORATE MONOHYDRATE
MI  
Systematic Name English
PERCHLORIC ACID, SODIUM SALT, MONOHYDRATE
Preferred Name English
SODIUM PERCHLORATE MONOHYDRATE [MI]
Common Name English
Code System Code Type Description
EVMPD
SUB28833
Created by admin on Mon Mar 31 20:20:12 GMT 2025 , Edited by admin on Mon Mar 31 20:20:12 GMT 2025
PRIMARY
PUBCHEM
202216
Created by admin on Mon Mar 31 20:20:12 GMT 2025 , Edited by admin on Mon Mar 31 20:20:12 GMT 2025
PRIMARY
EPA CompTox
DTXSID20228542
Created by admin on Mon Mar 31 20:20:12 GMT 2025 , Edited by admin on Mon Mar 31 20:20:12 GMT 2025
PRIMARY
SMS_ID
100000092527
Created by admin on Mon Mar 31 20:20:12 GMT 2025 , Edited by admin on Mon Mar 31 20:20:12 GMT 2025
PRIMARY
MERCK INDEX
m10054
Created by admin on Mon Mar 31 20:20:12 GMT 2025 , Edited by admin on Mon Mar 31 20:20:12 GMT 2025
PRIMARY Merck Index
CAS
7791-07-3
Created by admin on Mon Mar 31 20:20:12 GMT 2025 , Edited by admin on Mon Mar 31 20:20:12 GMT 2025
PRIMARY
FDA UNII
G4H485LHCW
Created by admin on Mon Mar 31 20:20:12 GMT 2025 , Edited by admin on Mon Mar 31 20:20:12 GMT 2025
PRIMARY
Related Record Type Details
Structure of PERCHLORIC ACID
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of PERCHLORATE ION
ACTIVE MOIETY
NIH
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