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Details

Stereochemistry ACHIRAL
Molecular Formula C14H16N2O.ClH
Molecular Weight 264.751
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of COUMAZOLINE HYDROCHLORIDE

SMILES

Cl.CCC1=C(CC2=NCCN2)C3=C(O1)C=CC=C3

InChI

InChIKey=YDDYHDKRIBOHOT-UHFFFAOYSA-N
InChI=1S/C14H16N2O.ClH/c1-2-12-11(9-14-15-7-8-16-14)10-5-3-4-6-13(10)17-12;/h3-6H,2,7-9H2,1H3,(H,15,16);1H

HIDE SMILES / InChI
Coumazoline is a vasoconstrictor developed as a nasal decongestant by a French corporation Labez. Intravenous administration of the compound to dogs lead to a marked and prolonged drop in the temperature of the gingival mucosa. In rats, coumazoline caused slowing of the dye diffusion on the surface of the skin. The compound did not influence the ciliary motility, as was measured on an isolated guinea pig trachea.

Approval Year

Name Type Language
COUMAZOLINE HYDROCHLORIDE
Common Name English
L-5818
Preferred Name English
1H-IMIDAZOLE, 2-((2-ETHYL-3-BENZOFURANYL)METHYL)-4,5-DIHYDRO-, HYDROCHLORIDE (1:1)
Systematic Name English
L5818
Code English
1H-IMIDAZOLE, 2-((2-ETHYL-3-BENZOFURANYL)METHYL)-4,5-DIHYDRO-, MONOHYDROCHLORIDE
Systematic Name English
2-((2-ETHYLBENZOFURAN-3-YL)METHYL)-2-IMIDAZOLINE
Systematic Name English
Code System Code Type Description
PUBCHEM
16205103
Created by admin on Mon Mar 31 18:03:02 GMT 2025 , Edited by admin on Mon Mar 31 18:03:02 GMT 2025
PRIMARY
ECHA (EC/EINECS)
253-670-3
Created by admin on Mon Mar 31 18:03:02 GMT 2025 , Edited by admin on Mon Mar 31 18:03:02 GMT 2025
PRIMARY
CAS
37795-09-8
Created by admin on Mon Mar 31 18:03:02 GMT 2025 , Edited by admin on Mon Mar 31 18:03:02 GMT 2025
PRIMARY
EPA CompTox
DTXSID20958837
Created by admin on Mon Mar 31 18:03:02 GMT 2025 , Edited by admin on Mon Mar 31 18:03:02 GMT 2025
PRIMARY
FDA UNII
U3P3Y52JKX
Created by admin on Mon Mar 31 18:03:02 GMT 2025 , Edited by admin on Mon Mar 31 18:03:02 GMT 2025
PRIMARY