COUMAZOLINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H16N2O.ClH
Molecular Weight	264.751
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCC1=C(CC2=NCCN2)C3=C(O1)C=CC=C3

InChI

InChIKey=YDDYHDKRIBOHOT-UHFFFAOYSA-N

InChI=1S/C14H16N2O.ClH/c1-2-12-11(9-14-15-7-8-16-14)10-5-3-4-6-13(10)17-12;/h3-6H,2,7-9H2,1H3,(H,15,16);1H

HIDE SMILES / InChI

Molecular Formula	C14H16N2O
Molecular Weight	228.2896
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://patents.google.com/patent/GB1333471A/en

Coumazoline is a vasoconstrictor developed as a nasal decongestant by a French corporation Labez. Intravenous administration of the compound to dogs lead to a marked and prolonged drop in the temperature of the gingival mucosa. In rats, coumazoline caused slowing of the dye diffusion on the surface of the skin. The compound did not influence the ciliary motility, as was measured on an isolated guinea pig trachea.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:36:55 GMT 2023` Edited by `admin` on `Fri Dec 15 15:36:55 GMT 2023`
Record UNII	U3P3Y52JKX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

COUMAZOLINE HYDROCHLORIDE

Common Name

English

1H-IMIDAZOLE, 2-((2-ETHYL-3-BENZOFURANYL)METHYL)-4,5-DIHYDRO-, HYDROCHLORIDE (1:1)

Systematic Name

English

L5818

Code

English

L-5818

Code

English

1H-IMIDAZOLE, 2-((2-ETHYL-3-BENZOFURANYL)METHYL)-4,5-DIHYDRO-, MONOHYDROCHLORIDE

Systematic Name

English

2-((2-ETHYLBENZOFURAN-3-YL)METHYL)-2-IMIDAZOLINE

Systematic Name

English

Code System Code Type Description

PUBCHEM

16205103