COUMAZOLINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H16N2O
Molecular Weight	228.2896
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC1=C(CC2=NCCN2)C3=C(O1)C=CC=C3

InChI

InChIKey=QZRIKRJFJVVUSF-UHFFFAOYSA-N

InChI=1S/C14H16N2O/c1-2-12-11(9-14-15-7-8-16-14)10-5-3-4-6-13(10)17-12/h3-6H,2,7-9H2,1H3,(H,15,16)

HIDE SMILES / InChI

Molecular Formula	C14H16N2O
Molecular Weight	228.2896
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://patents.google.com/patent/GB1333471A/en

Coumazoline is a vasoconstrictor developed as a nasal decongestant by a French corporation Labez. Intravenous administration of the compound to dogs lead to a marked and prolonged drop in the temperature of the gingival mucosa. In rats, coumazoline caused slowing of the dye diffusion on the surface of the skin. The compound did not influence the ciliary motility, as was measured on an isolated guinea pig trachea.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:10:40 GMT 2023` Edited by `admin` on `Fri Dec 15 16:10:40 GMT 2023`
Record UNII	TR7Y641235
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

COUMAZOLINE

Official Name

English

L 5818 FREE BASE

Code

English

L-5818 FREE BASE

Code

English

1H-IMIDAZOLE, 2-((2-ETHYL-3-BENZOFURANYL)METHYL)-4,5-DIHYDRO-

Systematic Name

English

coumazoline [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29709