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Details

Stereochemistry ACHIRAL
Molecular Formula C10H11ClF3N3
Molecular Weight 265.663
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ORG-12962

SMILES

FC(F)(F)C1=CC=C(N=C1Cl)N2CCNCC2

InChI

InChIKey=QZYYPQAYSFBKPW-UHFFFAOYSA-N
InChI=1S/C10H11ClF3N3/c11-9-7(10(12,13)14)1-2-8(16-9)17-5-3-15-4-6-17/h1-2,15H,3-6H2

HIDE SMILES / InChI

Description

Org-12962 was developed by Organon as a potent and selective Serotonin 5-HT(2C) receptor agonist. It was in clinical trial phase II for depression treatment, but the investigation was discontinued. In addition, was shown, Org-12962 displayed antiaversive effects in a rat model of panic-like anxiety.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
7.01 null [pEC50]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown