Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H11ClF3N3.ClH |
| Molecular Weight | 302.124 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.FC(F)(F)C1=CC=C(N=C1Cl)N2CCNCC2
InChI
InChIKey=FVDILXYXZAAJOS-UHFFFAOYSA-N
InChI=1S/C10H11ClF3N3.ClH/c11-9-7(10(12,13)14)1-2-8(16-9)17-5-3-15-4-6-17;/h1-2,15H,3-6H2;1H
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C10H11ClF3N3 |
| Molecular Weight | 265.663 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Org-12962 was developed by Organon as a potent and selective Serotonin 5-HT(2C) receptor agonist. It was in clinical trial phase II for depression treatment, but the investigation was discontinued. In addition, was shown, Org-12962 displayed antiaversive effects in a rat model of panic-like anxiety.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Antiaversive effects of 5HT2C receptor agonists and fluoxetine in a model of panic-like anxiety in rats. | 1998 Aug |
|
| Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. | 2004 Aug |
|
| Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity. | 2005 Mar |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 19:30:18 GMT 2023
by
admin
on
Sat Dec 16 19:30:18 GMT 2023
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| Record UNII |
PZ5RGN8MR8
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| Record Status |
Validated (UNII)
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| Record Version |
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PZ5RGN8MR8
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9796407
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DTXSID60430869
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210821-63-9
Created by
admin on Sat Dec 16 19:30:18 GMT 2023 , Edited by admin on Sat Dec 16 19:30:18 GMT 2023
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
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