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Details

Stereochemistry RACEMIC
Molecular Formula C16H33NO2.ClH
Molecular Weight 307.9002
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DELMOPINOL HYDROCHLORIDE

SMILES

CCCC(CCC)CCCC1COCCN1CCO.Cl

InChI

InChIKey=JFZBMJJFVBMZNC-UHFFFAOYSA-N
InChI=1S/C16H33NO2.ClH/c1-3-6-15(7-4-2)8-5-9-16-14-19-13-11-17(16)10-12-18;/h15-16,18H,3-14H2,1-2H3;1H

HIDE SMILES / InChI
Delmopinol, a surface-active cationic agent. It was approved by FDA under the name Decapinol for the treatment of gingivitis and prevention of periodontitis. The drug interacts with the early acquired pellicle, the thin layer of saliva polymers and proteins covering teeth and gums, and forms a barrier over teeth and gums. This barrier prevents the microbial adhesion and colonisation on the tooth and gum surface. Delmopinol itself has no bactericidal activity.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
DECAPINOL

Approved Use

DECAPINOL is a novel, first in class, medical device to help treat gingivitis and prevent periodontitis by preventing the plaque formation on the teeth’s and gum’s surface.

Launch Date

1078358400000
Preventing
DECAPINOL

Approved Use

DECAPINOL is a novel, first in class, medical device to help treat gingivitis and prevent periodontitis by preventing the plaque formation on the teeth’s and gum’s surface.

Launch Date

1078358400000
PubMed

PubMed

TitleDatePubMed
Patents

Sample Use Guides

Mouthwash formulation: Rinse 10ml of delmopinol (Decapinol mouthwash) for 30 sec and expectorate, use twice a day, avoid eating and drinking for about 30 minutes after the use of the mouthwash. Toothpaste formulation: Brush your teeth with delmopinol (decapinol toothpaste) as instructed by your dental professional.
Route of Administration: Dental
Bacteria isolated from samples of human dental plaque were treated with delmopinol mouthwash. Different dilutions of the delmopinol (100%, 50%, 25%, 12.5%, 6.25%, 3.12%, 1.56%, 0.78%, 0.39%, 0.19%) were tested to determine the MIC of bacterial growth. MIC values were 0.78% for Streptococcus mutants, 1.56% for Lactobacillus and 6.25 and 3.12 for aerobic and anaerobic bacterias, respectively.
Name Type Language
DELMOPINOL HYDROCHLORIDE
MI  
Common Name English
DECAPINOL
Brand Name English
DELMOPINOL HCL
INCI  
INCI  
Official Name English
4-MORPHOLINEETHANOL, 3-(4-PROPYLHEPTYL)-, HYDROCHLORIDE
Systematic Name English
DELMOPINOL HCL [INCI]
Common Name English
M-1650
Code English
DELMOPINOL HYDROCHLORIDE [MI]
Common Name English
4-MORPHOLINEETHANOL, 3-(4-PROPYLHEPTYL)-, HYDROCHLORIDE (1:1)
Systematic Name English
Code System Code Type Description
FDA UNII
SRE423V9Z9
Created by admin on Sat Jun 26 10:30:04 UTC 2021 , Edited by admin on Sat Jun 26 10:30:04 UTC 2021
PRIMARY
PUBCHEM
6917873
Created by admin on Sat Jun 26 10:30:04 UTC 2021 , Edited by admin on Sat Jun 26 10:30:04 UTC 2021
PRIMARY
CAS
98092-92-3
Created by admin on Sat Jun 26 10:30:04 UTC 2021 , Edited by admin on Sat Jun 26 10:30:04 UTC 2021
PRIMARY
MERCK INDEX
M4154
Created by admin on Sat Jun 26 10:30:04 UTC 2021 , Edited by admin on Sat Jun 26 10:30:04 UTC 2021
PRIMARY Merck Index