FAMOTINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H14ClNO
Molecular Weight	271.741
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FAMOTINE

Structure Search

SMILES

ClC1=CC=C(OCC2=NCCC3=CC=CC=C23)C=C1

InChI

InChIKey=YHDHSSBAHPSMPM-UHFFFAOYSA-N

InChI=1S/C16H14ClNO/c17-13-5-7-14(8-6-13)19-11-16-15-4-2-1-3-12(15)9-10-18-16/h1-8H,9-11H2

HIDE SMILES / InChI

Description
Sources: https://link.springer.com/chapter/10.1007/978-1-4757-2085-3_6 | https://www.ncbi.nlm.nih.gov/pubmed/5309492 | https://www.ncbi.nlm.nih.gov/pubmed/4185593

Famotine, 1 -(p-chlorophenoxymethyl)-3,4-dihydroisoquinoline (UK 2054), is an antiviral compound.

Approval Year

PubMed

PubMed

Title	Date	PubMed
The antiviral activity of the isoquinolines famotine and memotine in respiratory infections in man.	1969	5309492
Prophylaxis of influenza B with UK 2054.	1969 Sep 20	4185593
A QSAR study on influenza neuraminidase inhibitors.	2006 Feb 15	16213733

Name

Type

Language

FAMOTINE

Official Name

English

ISOQUINOLINE, 1-((4-CHLOROPHENOXY)METHYL)-3,4-DIHYDRO-

Systematic Name

English

1-((P-CHLOROPHENOXY)METHYL)-3,4-DIHYDROISOQUINOLINE

Common Name

English

famotine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C281

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL2110933

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

PUBCHEM

29069

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

CAS

18429-78-2

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

INN

2691

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

FDA UNII

SJ6B3W3NWD

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

EVMPD

SUB07504MIG

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

MESH

C000435

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

NCI_THESAURUS

C76495

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

SMS_ID

100000081554

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

EPA CompTox

DTXSID90171556

Created by admin on Fri Dec 15 15:20:45 UTC 2023 , Edited by admin on Fri Dec 15 15:20:45 UTC 2023

PRIMARY

ACTIVE MOIETY


					SJ6B3W3NWD

FAMOTINE

SALT/SOLVATE (PARENT)


					7L9H348XUO

FAMOTINE HYDROCHLORIDE