FAMOTINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H14ClNO
Molecular Weight	271.741
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FAMOTINE

Structure Search

SMILES

ClC1=CC=C(OCC2=NCCC3=C2C=CC=C3)C=C1

InChI

InChIKey=YHDHSSBAHPSMPM-UHFFFAOYSA-N

InChI=1S/C16H14ClNO/c17-13-5-7-14(8-6-13)19-11-16-15-4-2-1-3-12(15)9-10-18-16/h1-8H,9-11H2

HIDE SMILES / InChI

Molecular Formula	C16H14ClNO
Molecular Weight	271.741
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://link.springer.com/chapter/10.1007/978-1-4757-2085-3_6 | https://www.ncbi.nlm.nih.gov/pubmed/5309492 | https://www.ncbi.nlm.nih.gov/pubmed/4185593

Famotine, 1 -(p-chlorophenoxymethyl)-3,4-dihydroisoquinoline (UK 2054), is an antiviral compound.

Approval Year

PubMed

PubMed

Title	Date	PubMed
A QSAR study on influenza neuraminidase inhibitors.	2006-02-15	16213733
Prophylaxis of influenza B with UK 2054.	1969-09-20	4185593
The antiviral activity of the isoquinolines famotine and memotine in respiratory infections in man.	1969	5309492

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:54:44 GMT 2025` Edited by `admin` on `Mon Mar 31 17:54:44 GMT 2025`
Record UNII	SJ6B3W3NWD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-((P-CHLOROPHENOXY)METHYL)-3,4-DIHYDROISOQUINOLINE

Preferred Name

English

FAMOTINE

Official Name

English

ISOQUINOLINE, 1-((4-CHLOROPHENOXY)METHYL)-3,4-DIHYDRO-

Systematic Name

English

famotine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C281

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

Code System Code Type Description

ChEMBL

CHEMBL2110933

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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PUBCHEM

29069

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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CAS

18429-78-2

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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INN

2691

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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FDA UNII

SJ6B3W3NWD

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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EVMPD

SUB07504MIG

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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MESH

C000435

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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NCI_THESAURUS

C76495

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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SMS_ID

100000081554

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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EPA CompTox

DTXSID90171556

Created by admin on Mon Mar 31 17:54:44 GMT 2025 , Edited by admin on Mon Mar 31 17:54:44 GMT 2025

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					7L9H348XUO

FAMOTINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

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					SJ6B3W3NWD

FAMOTINE

ACTIVE MOIETY