FAMOTINE HYDROCHLORIDE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H14ClNO.ClH
Molecular Weight	308.202
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FAMOTINE HYDROCHLORIDE

Structure Search

SMILES

Cl.ClC1=CC=C(OCC2=NCCC3=C2C=CC=C3)C=C1

InChI

InChIKey=XWPQCMLTRJWFKB-UHFFFAOYSA-N

InChI=1S/C16H14ClNO.ClH/c17-13-5-7-14(8-6-13)19-11-16-15-4-2-1-3-12(15)9-10-18-16;/h1-8H,9-11H2;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C16H14ClNO
Molecular Weight	271.741
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://link.springer.com/chapter/10.1007/978-1-4757-2085-3_6 | https://www.ncbi.nlm.nih.gov/pubmed/5309492 | https://www.ncbi.nlm.nih.gov/pubmed/4185593

Famotine, 1 -(p-chlorophenoxymethyl)-3,4-dihydroisoquinoline (UK 2054), is an antiviral compound.

Approval Year

PubMed

PubMed

Title	Date	PubMed
A QSAR study on influenza neuraminidase inhibitors.	2006-02-15	16213733
Prophylaxis of influenza B with UK 2054.	1969-09-20	4185593
The antiviral activity of the isoquinolines famotine and memotine in respiratory infections in man.	1969	5309492

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:35:58 GMT 2025` Edited by `admin` on `Mon Mar 31 17:35:58 GMT 2025`
Record UNII	7L9H348XUO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-139353

Preferred Name

English

FAMOTINE HYDROCHLORIDE

Official Name

English

UK-2054

Code

English

FAMOTINE HCL

Common Name

English

FAMOTINE HYDROCHLORIDE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C281

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

Code System Code Type Description

SMS_ID

300000055493

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

PRIMARY

MESH

C000435

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

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NCI_THESAURUS

C77927

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

PRIMARY

ChEMBL

CHEMBL2110933

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

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PUBCHEM

208950

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

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CAS

10500-82-0

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

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NSC

139353

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

PRIMARY

EPA CompTox

DTXSID00146912

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

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FDA UNII

7L9H348XUO

Created by admin on Mon Mar 31 17:35:58 GMT 2025 , Edited by admin on Mon Mar 31 17:35:58 GMT 2025

PRIMARY

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