FAMOTINE HYDROCHLORIDE

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H14ClNO.ClH
Molecular Weight	308.202
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FAMOTINE HYDROCHLORIDE

Structure Search

SMILES

Cl.ClC1=CC=C(OCC2=NCCC3=CC=CC=C23)C=C1

InChI

InChIKey=XWPQCMLTRJWFKB-UHFFFAOYSA-N

InChI=1S/C16H14ClNO.ClH/c17-13-5-7-14(8-6-13)19-11-16-15-4-2-1-3-12(15)9-10-18-16;/h1-8H,9-11H2;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C16H14ClNO
Molecular Weight	271.741
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://link.springer.com/chapter/10.1007/978-1-4757-2085-3_6 | https://www.ncbi.nlm.nih.gov/pubmed/5309492 | https://www.ncbi.nlm.nih.gov/pubmed/4185593

Famotine, 1 -(p-chlorophenoxymethyl)-3,4-dihydroisoquinoline (UK 2054), is an antiviral compound.

Approval Year

PubMed

PubMed

Title	Date	PubMed
The antiviral activity of the isoquinolines famotine and memotine in respiratory infections in man.	1969	5309492
Prophylaxis of influenza B with UK 2054.	1969 Sep 20	4185593
A QSAR study on influenza neuraminidase inhibitors.	2006 Feb 15	16213733

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:01:55 UTC 2023` Edited by `admin` on `Fri Dec 15 15:01:55 UTC 2023`
Record UNII	7L9H348XUO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FAMOTINE HYDROCHLORIDE

Official Name

English

UK-2054

Code

English

FAMOTINE HCL

Common Name

English

NSC-139353

Code

English

FAMOTINE HYDROCHLORIDE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C281

Created by admin on Fri Dec 15 15:01:55 UTC 2023 , Edited by admin on Fri Dec 15 15:01:55 UTC 2023

Code System Code Type Description

MESH

C000435

Created by admin on Fri Dec 15 15:01:55 UTC 2023 , Edited by admin on Fri Dec 15 15:01:55 UTC 2023

PRIMARY

NCI_THESAURUS

C77927

Created by admin on Fri Dec 15 15:01:55 UTC 2023 , Edited by admin on Fri Dec 15 15:01:55 UTC 2023

PRIMARY

ChEMBL

CHEMBL2110933

Created by admin on Fri Dec 15 15:01:55 UTC 2023 , Edited by admin on Fri Dec 15 15:01:55 UTC 2023

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PUBCHEM

208950

Created by admin on Fri Dec 15 15:01:55 UTC 2023 , Edited by admin on Fri Dec 15 15:01:55 UTC 2023

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CAS

10500-82-0

Created by admin on Fri Dec 15 15:01:55 UTC 2023 , Edited by admin on Fri Dec 15 15:01:55 UTC 2023

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NSC

139353

Created by admin on Fri Dec 15 15:01:55 UTC 2023 , Edited by admin on Fri Dec 15 15:01:55 UTC 2023

PRIMARY

EPA CompTox

DTXSID00146912

Created by admin on Fri Dec 15 15:01:55 UTC 2023 , Edited by admin on Fri Dec 15 15:01:55 UTC 2023

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FDA UNII

7L9H348XUO

Created by admin on Fri Dec 15 15:01:55 UTC 2023 , Edited by admin on Fri Dec 15 15:01:55 UTC 2023

PRIMARY

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