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Details

Stereochemistry ACHIRAL
Molecular Formula C12H12NO4S.Na
Molecular Weight 289.283
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALADORIAN SODIUM

SMILES

[Na+].COC1=CC=C2SCCN(CC2=C1)C(=O)C([O-])=O

InChI

InChIKey=OUNBYSZUAWDKLT-UHFFFAOYSA-M
InChI=1S/C12H13NO4S.Na/c1-17-9-2-3-10-8(6-9)7-13(4-5-18-10)11(14)12(15)16;/h2-3,6H,4-5,7H2,1H3,(H,15,16);/q;+1/p-1

HIDE SMILES / InChI
ARMGO and Servier are developing an anti-arrhythmia drug aladorian (ARM036) for the treatment of heart failure, arrhythmia and ventricular tachycardia. Aladorian was the first in-house discovered, novel, small molecule NCE (Rycal®) from ARMGO’s library that was advanced into clinical studies. ARM036 completed multiple Phase IIa clinical studies in chronic heart failure patients, demonstrating positive activity and safety in patients, and validating ARMGO’s approach for drug discovery and candidate selection on the RyR target.

Approval Year

PubMed

PubMed

TitleDatePubMed
Analytical approaches for the detection of emerging therapeutics and non-approved drugs in human doping controls.
2014 Dec
Patents

Sample Use Guides

Rats: 1.11 mg/kg/day ARM036 given via osmotic pump
Route of Administration: Oral
Name Type Language
ALADORIAN SODIUM
USAN   WHO-DD  
USAN  
Official Name English
S36NA
Code English
S-44121-2
Code English
S-36 NA
Code English
S44121-2
Code English
Aladorian sodium [WHO-DD]
Common Name English
ARM-036 NA
Code English
ALADORIAN SODIUM [USAN]
Common Name English
ARM036NA
Code English
Classification Tree Code System Code
NCI_THESAURUS C47793
Created by admin on Fri Dec 15 17:22:16 GMT 2023 , Edited by admin on Fri Dec 15 17:22:16 GMT 2023
Code System Code Type Description
CAS
1233219-11-8
Created by admin on Fri Dec 15 17:22:16 GMT 2023 , Edited by admin on Fri Dec 15 17:22:16 GMT 2023
PRIMARY
USAN
YY-113
Created by admin on Fri Dec 15 17:22:16 GMT 2023 , Edited by admin on Fri Dec 15 17:22:16 GMT 2023
PRIMARY
SMS_ID
300000044547
Created by admin on Fri Dec 15 17:22:16 GMT 2023 , Edited by admin on Fri Dec 15 17:22:16 GMT 2023
PRIMARY
ChEMBL
CHEMBL2104951
Created by admin on Fri Dec 15 17:22:16 GMT 2023 , Edited by admin on Fri Dec 15 17:22:16 GMT 2023
PRIMARY
EPA CompTox
DTXSID90153953
Created by admin on Fri Dec 15 17:22:16 GMT 2023 , Edited by admin on Fri Dec 15 17:22:16 GMT 2023
PRIMARY
NCI_THESAURUS
C142906
Created by admin on Fri Dec 15 17:22:16 GMT 2023 , Edited by admin on Fri Dec 15 17:22:16 GMT 2023
PRIMARY
FDA UNII
RF69WW39TI
Created by admin on Fri Dec 15 17:22:16 GMT 2023 , Edited by admin on Fri Dec 15 17:22:16 GMT 2023
PRIMARY
PUBCHEM
56640724
Created by admin on Fri Dec 15 17:22:16 GMT 2023 , Edited by admin on Fri Dec 15 17:22:16 GMT 2023
PRIMARY