ALADORIAN SODIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H12NO4S.Na
Molecular Weight	289.283
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].COC1=CC=C2SCCN(CC2=C1)C(=O)C([O-])=O

InChI

InChIKey=OUNBYSZUAWDKLT-UHFFFAOYSA-M

InChI=1S/C12H13NO4S.Na/c1-17-9-2-3-10-8(6-9)7-13(4-5-18-10)11(14)12(15)16;/h2-3,6H,4-5,7H2,1H3,(H,15,16);/q;+1/p-1

HIDE SMILES / InChI

Molecular Formula	C12H12NO4S
Molecular Weight	266.293
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://adisinsight.springer.com/drugs/800034371 | http://www.armgo.com/pipeline.html

ARMGO and Servier are developing an anti-arrhythmia drug aladorian (ARM036) for the treatment of heart failure, arrhythmia and ventricular tachycardia. Aladorian was the first in-house discovered, novel, small molecule NCE (Rycal®) from ARMGO’s library that was advanced into clinical studies. ARM036 completed multiple Phase IIa clinical studies in chronic heart failure patients, demonstrating positive activity and safety in patients, and validating ARMGO’s approach for drug discovery and candidate selection on the RyR target.

Originator

Approval Year

PubMed

Title	Date	PubMed
Analytical approaches for the detection of emerging therapeutics and non-approved drugs in human doping controls.	2014-12	24906629

Patents

Sample Use Guides

In Vivo Use Guide

Rats: 1.11 mg/kg/day ARM036 given via osmotic pump

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:45:25 GMT 2025` Edited by `admin` on `Mon Mar 31 18:45:25 GMT 2025`
Record UNII	RF69WW39TI
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ALADORIAN SODIUM

Official Name

English

ARM-036 NA

Preferred Name

English

S36NA

Code

English

S-44121-2

Code

English

S-36 NA

Code

English

S44121-2

Code

English

Aladorian sodium [WHO-DD]

Common Name

English

ALADORIAN SODIUM [USAN]

Common Name

English

ARM036NA

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C47793