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Details

Stereochemistry ACHIRAL
Molecular Formula C10H18N2O7
Molecular Weight 278.2591
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID

SMILES

OCCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

InChIKey=URDCARMUOSMFFI-UHFFFAOYSA-N
InChI=1S/C10H18N2O7/c13-4-3-11(5-8(14)15)1-2-12(6-9(16)17)7-10(18)19/h13H,1-7H2,(H,14,15)(H,16,17)(H,18,19)

HIDE SMILES / InChI
HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID (HEDTA) is used in cosmetics and care products. It’s a chelating agent, which in combination with selenium was effective in reducing the concentration of Al and level of DNA damage. In addition, experiments with rodents have shown that combination of HEDTA and propolis preserved histological features, mitigated oxidative stress and improved liver, kidney, and brain functions more profoundly.

Approval Year

PubMed

PubMed

TitleDatePubMed
Inhibition of CaT1 channel activity by a noncompetitive IP3 antagonist.
2001 Jan 12
High-pressure pulse-radiolysis study of the formation and decomposition of complexes with iron-carbon sigma bonds: mechanistic comparison for different metal centers.
2001 Sep 10
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTA.
2002
Determination of strong binding chelators and their metal complexes by anion-exchange chromatography and inductively coupled plasma mass spectrometry.
2002 Feb 22
Effect of N-hydroxyethyl-ethylenediamine-triacetic acid (HEDTA) on Cr(VI) reduction by Fe(II).
2003 Jun
Aluminum-induced oxidative stress in rat brain: response to combined administration of citric acid and HEDTA.
2003 Mar
Isothermal titration calorimetric procedure to determine protein-metal ion binding parameters in the presence of excess metal ion or chelator.
2003 Mar 15
Biogeochemistry of fluoride in a plant-solution system.
2003 Nov-Dec
The [Ru(Hedta)NO](0.1-) system: structure, chemical reactivity and biological assays.
2004 Nov
Neutrophil secretion induced by an intracellular Ca2+ rise and followed by whole-cell patch-clamp recordings occurs without any selective mobilization of different granule populations.
2006
Improving sensitivity in simultaneous determination of copper carboxylates by nonaqueous capillary electrophoresis.
2006 Mar 31
Separation of chelating agents as copper complexes by capillary zone electrophoresis using quaternary ammonium bromides as additives in N-methylformamide.
2006 Oct 27
Solubility and accumulation of metals in Chinese brake fern, vetiver and rostrate sesbania using chelating agents.
2007 Jul-Aug
Determination of sequestering agents in cosmetics and synthetic detergents by high-performance liquid chromatography with ultraviolet detection.
2007 Nov 9
Limits of calcium clearance by plasma membrane calcium ATPase in olfactory cilia.
2009
Speciation of Zn-aminopolycarboxylic complexes by electrospray ionization mass spectrometry and ion chromatography with inductively coupled plasma mass spectrometry.
2009 Feb
A novel manganese complex effective as superoxide anion scavenger and therapeutic agent against cell and tissue oxidative injury.
2009 Nov 26
Development of a novel aluminum tolerance phenotyping platform used for comparisons of cereal aluminum tolerance and investigations into rice aluminum tolerance mechanisms.
2010 Aug
Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4.
2010 May 11
Name Type Language
HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID
HSDB  
Common Name English
HEDTA
INCI  
INCI  
Official Name English
N-HYDROXYETHYL ETHYLENEDIAMINE TRIACETIC ACID
Systematic Name English
HYDROXYETHYLETHYLENEDIAMINETRIACETIC ACID [HSDB]
Common Name English
HEDTA [INCI]
Common Name English
N-(2-HYDROXYETHYL)ETHYLENEDIAMINETRIACETIC ACID
Common Name English
NSC-7341
Code English
N-(2-HYDROXYETHYL)ETHYLENEDIAMINE-N,N',N'-TRIACETIC ACID
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 39108
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
Code System Code Type Description
NSC
7341
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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HSDB
5651
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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RXCUI
1364568
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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DAILYMED
R79J91U341
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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CAS
150-39-0
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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FDA UNII
R79J91U341
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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MESH
C026060
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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PUBCHEM
8773
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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EPA CompTox
DTXSID1059737
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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ECHA (EC/EINECS)
205-759-3
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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WIKIPEDIA
Hydroxyethylethylenediaminetriacetic acid
Created by admin on Fri Dec 15 15:02:04 GMT 2023 , Edited by admin on Fri Dec 15 15:02:04 GMT 2023
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