DIHYDROETORPHINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C25H35NO4
Molecular Weight	413.5497
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC[C@@](C)(O)[C@H]1C[C@@]23CC[C@]1(OC)[C@@H]4OC5=C(O)C=CC6=C5[C@]24CCN(C)[C@@H]3C6

InChI

InChIKey=BRTSNYPDACNMIP-FAWZKKEFSA-N

InChI=1S/C25H35NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,17-18,21,27-28H,5,8-14H2,1-4H3/t17-,18-,21-,22-,23-,24+,25-/m1/s1

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
The orvinols and related opioids--high affinity ligands with diverse efficacy profiles.	2004	15032698
Tramadol and dihydroetorphine produce synergistic analgesic effect and postpones acute opiate tolerance in rats.	2005 Dec 25	16344893
Paradoxical relationship between RAVE (relative activity versus endocytosis) values of several opioid receptor agonists and their liability to cause dependence.	2010 Apr	20228826

Name

Type

Language

IDS-ND-025

Preferred Name

English

DIHYDROETORPHINE

Common Name

English

TETRAHYDRO-7.ALPHA.-(1-HYDROXY-1-METHYLBUTYL)-6,14-ENDO-ETHANOORIPAVINE

Common Name

English

Dihydroetorphine [WHO-DD]

Common Name

English

6,14-ETHENOMORPHINAN-7-METHANOL, 4,5-EPOXY-18,19-DIHYDRO-3-HYDROXY-6-METHOXY-.ALPHA.,17-DIMETHYL-.ALPHA.-PROPYL-, (.ALPHA.R,5.ALPHA.,7.ALPHA.)

Common Name

English

7,8-DIHYDRO-7.ALPHA.-(1-(R)-HYDROXY-1-METHYLBUTYL)-6,14-ENDOETHANOTETRAHYDROORIPAVINE

Systematic Name

English

R-dihydroetorphine

Common Name

English

Classification Tree Code System Code

DEA NO.

9334