U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Description

Eledoisin is an endecapeptide tachykinin receptor ligand. Originally it was isolated from salivary glands of Mediterranean octopod, Eledone moschata. Eledoisin is a powerful vasodilator and hypotensive agent in most animal species.

Originator

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
The unpredicted high affinities of a large number of naturally occurring tachykinins for chimeric NK1/NK3 receptors suggest a role for an inhibitory domain in determining receptor specificity.
1996-08-23
Molecular characterisation, expression and localisation of human neurokinin-3 receptor.
1992-03-24
Patents

Patents

JP2003502364A
6
JPS6193195A
3
Name Type Language
ELEDOISIN
INN   MART.   MI   WHO-DD  
INN  
Official Name English
ELD 950
Preferred Name English
ELEDOISIN [MART.]
Common Name English
PGLU-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
Common Name English
5-OXO-L-PROLYL-L-PROLYL-L-SERYL-L-LYSYL-L-ASPARTYL-L-ALANYL-L-PHENYLALANYL-L-ISOLEUCYLGLYCYL-L-LEUCYL-L-METHIONINAMIDE
Common Name English
5-OXOPRO-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
Common Name English
ELD-950
Code English
Eledoisin [WHO-DD]
Common Name English
eledoisin [INN]
Common Name English
ELEDOISIN [MI]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C894
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
Code System Code Type Description
CAS
69-25-0
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
MERCK INDEX
m4858
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY Merck Index
NCI_THESAURUS
C80866
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
EPA CompTox
DTXSID1046926
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
FDA UNII
OKY3285J18
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
WIKIPEDIA
ELEDOISIN
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
SMS_ID
100000080541
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
INN
3278
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
PUBCHEM
10328936
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
ChEMBL
CHEMBL373569
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
EVMPD
SUB06481MIG
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
DRUG CENTRAL
2955
Created by admin on Mon Mar 31 18:14:58 GMT 2025 , Edited by admin on Mon Mar 31 18:14:58 GMT 2025
PRIMARY
ACTIVE MOIETY
ELEDOISIN
SALT/SOLVATE (PARENT)
ELEDOISIN TRIFLUOROACETATE
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966