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Description

Eledoisin is an endecapeptide tachykinin receptor ligand. Originally it was isolated from salivary glands of Mediterranean octopod, Eledone moschata. Eledoisin is a powerful vasodilator and hypotensive agent in most animal species.

Originator

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
The unpredicted high affinities of a large number of naturally occurring tachykinins for chimeric NK1/NK3 receptors suggest a role for an inhibitory domain in determining receptor specificity.
1996-08-23
Molecular characterisation, expression and localisation of human neurokinin-3 receptor.
1992-03-24
Patents

Patents

JP2003502364A
6
JPS6193195A
3
Substance Class Protein
Created
by admin
on Tue Apr 01 19:47:04 GMT 2025
Edited
by admin
on Tue Apr 01 19:47:04 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
T9L8F7448X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ELOISIN
Preferred Name English
ELEDOISIN TRIFLUOROACETATE
MI   WHO-DD  
Common Name English
Eledoisin trifluoroacetate [WHO-DD]
Common Name English
5-OXO-L-PROLYL-L-PROLYL-L-SERYL-L-LYSYL-L-ASPARTYL-L-ALANYL-L-PHENYLALANYL-L-ISOLEUCYLGLYCYL-L-LEUCYL-L-METHIONINAMIDE TRIFLUOROACETATE
Common Name English
ACETIC ACID, TRIFLUORO-, COMPD. WITH ELEDOISIN (1:1)
Common Name English
ELEDOISIN TRIFLUORACETATE
Common Name English
ELEDOISIN TRIFLUOROACETATE [MI]
Common Name English
ELEDOISIN, MONO(TRIFLUOROACETATE) (SALT)
Common Name English
Code System Code Type Description
SMS_ID
100000087336
Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025
PRIMARY
CAS
10129-92-7
Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025
PRIMARY
EPA CompTox
DTXSID901021509
Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025
PRIMARY
FDA UNII
T9L8F7448X
Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025
PRIMARY
PUBCHEM
91667949
Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025
PRIMARY
EVMPD
SUB21006
Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025
PRIMARY
MERCK INDEX
m4858
Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025
PRIMARY Merck Index
Related Record Type Details
ELEDOISIN
PARENT -> SALT/SOLVATE
ELEDOISIN
STARTING MATERIAL -> INGREDIENT
Related Record Type Details
ELEDOISIN
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
SALT FORMATION CHEMICAL Trifluoroacetic acid E5R8Z4G708

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID SUBSTITUION [1_1] PROLINE PIDOLIC ACID SZB83O1W42
AMINO ACID SUBSTITUION [1_11] METHIONINE METHIONINAMIDE QSM06A70MD
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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