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Details

Stereochemistry ACHIRAL
Molecular Formula C15H24N2O2
Molecular Weight 264.3633
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIMETHOLIZINE

SMILES

COCCCN1CCN(CC1)C2=CC=CC=C2OC

InChI

InChIKey=ITNSQDCAZVVFMS-UHFFFAOYSA-N
InChI=1S/C15H24N2O2/c1-18-13-5-8-16-9-11-17(12-10-16)14-6-3-4-7-15(14)19-2/h3-4,6-7H,5,8-13H2,1-2H3

HIDE SMILES / InChI

Description

Dimetholizine has antihypertensive activity. It is an antihistaminic agent too. Histamine H1 receptor was predicted as a primary target for dimetholizine. Moreover, it was found to bind the Dopamine D2 and 5-HT1A receptors. Dimetholizine was predicted to be alpha1D-Adrenergic blocker.

Approval Year

Unknown
139594
Patents

Patents

20100226943
185
Name Type Language
DIMETHOLIZINE
INN  
INN  
Official Name English
1-(O-METHOXYPHENYL)-4-(3-METHOXYPROPYL)PIPERAZINE
Common Name English
dimetholizine [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29578
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
Code System Code Type Description
EVMPD
SUB07174MIG
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
PRIMARY
ChEMBL
CHEMBL2106630
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
PRIMARY
INN
914
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
PRIMARY
PUBCHEM
208842
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
PRIMARY
NCI_THESAURUS
C65405
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
PRIMARY
SMS_ID
100000082643
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
PRIMARY
CAS
7008-00-6
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
PRIMARY
FDA UNII
O6U9W3DMYT
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
PRIMARY
EPA CompTox
DTXSID201024457
Created by admin on Fri Dec 15 16:22:00 GMT 2023 , Edited by admin on Fri Dec 15 16:22:00 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of DIMETHOLIZINE
SALT/SOLVATE (PARENT)
Structure of DIMETHOLIZINE PHOSPHATE
NIH
NCATS
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