OLEZARSEN SODIUM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Name

Type

Language

OLEZARSEN SODIUM

Official Name

English

D(P-THIO)((2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M 5RU-M5C-T-T-G-T-M5C-M5C-A-G-M5C-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))

Preferred Name

English

ALL-P-AMBO-5'-O-(((6-(5-((TRIS(3-(6-(2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYLOXY)HEXYLAMINO)-3-OXOPROPOXYMETHYL))METHYL)AMINO-5-OXOPENTANAMIDO)HEXYL))PHOSPHO)-2'-O-(2-METHOXYETHYL)-P-THIOADENYLYL-(3'-O->5'-O)-2'-O-(2-METHOXYETHYL)-P-THIOGUANYLYL-(3'

Systematic Name

English

TRYNGOLZA

Brand Name

English

ISIS-678354 SODIUM

Code

English

IONIS-APOCIII-LRX, SODIUM

Code

English

OLEZARSEN SODIUM [USAN]

Common Name

English

Code System Code Type Description

FDA UNII

NSY2BY6PSB

Created by admin on Wed Apr 02 11:29:00 GMT 2025 , Edited by admin on Wed Apr 02 11:29:00 GMT 2025

PRIMARY

USAN

HI-30

Created by admin on Wed Apr 02 11:29:00 GMT 2025 , Edited by admin on Wed Apr 02 11:29:00 GMT 2025

PRIMARY

NCI_THESAURUS

C180653

Created by admin on Wed Apr 02 11:29:00 GMT 2025 , Edited by admin on Wed Apr 02 11:29:00 GMT 2025

PRIMARY

SMS_ID

300000018714

Created by admin on Wed Apr 02 11:29:00 GMT 2025 , Edited by admin on Wed Apr 02 11:29:00 GMT 2025

PRIMARY

CAS

2298451-31-5

Created by admin on Wed Apr 02 11:29:00 GMT 2025 , Edited by admin on Wed Apr 02 11:29:00 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20
Deoxyribose (DNA)	1_6-1_15	10 / 20

Linkage	Site Range	Site Count
Sodium Phosporothioate	1_2-1_20	19 / 19

ACTIVE MOIETY


					S3RS2SA30L

OLEZARSEN

SUBSTANCE RECORD


					NSY2BY6PSB

OLEZARSEN SODIUM