OLEZARSEN

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 11:35:26 GMT 2025` Edited by `admin` on `Wed Apr 02 11:35:26 GMT 2025`
Nucleic Acid Type	OLIGONUCLEOTIDE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	S3RS2SA30L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AKCEA-APOCIII-LRX

Preferred Name

English

OLEZARSEN

Official Name

English

ISIS-678354

Code

English

Olezarsen [WHO-DD]

Common Name

English

olezarsen [INN]

Common Name

English

OLEZARSEN [USAN]

Common Name

English

IONIS-APOCIII-LRX

Code

English

ALL-P-AMBO-5'-O-(((6-(5-((TRIS(3-(6-(2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYLOXY)HEXYLAMINO)-3-OXOPROPOXYMETHYL))METHYL)AMINO-5-OXOPENTANAMIDO)HEXYL))PHOSPHO)-2'-O-(2-METHOXYETHYL)-P-THIOADENYLYL-(3'-O->5'-O)-2'-O-(2-METHOXYETHYL)-P-THIOGUANYLYL-(3'

Systematic Name

English

DNA, D(P-THIO)((2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-M5C-T-T-G-T-M5C-M5C-A-G-M5C-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETH

Common Name

English

ISIS-APOCIII-LRX

Code

English

Code System Code Type Description

SMS_ID

300000039030