IODOXAMIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H26I6N2O10
Molecular Weight	1287.9189
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C1=C(I)C=C(I)C(NC(=O)CCOCCOCCOCCOCCC(=O)NC2=C(I)C=C(I)C(C(O)=O)=C2I)=C1I

InChI

InChIKey=WWVAPFRKZMUPHZ-UHFFFAOYSA-N

InChI=1S/C26H26I6N2O10/c27-13-11-15(29)23(21(31)19(13)25(37)38)33-17(35)1-3-41-5-7-43-9-10-44-8-6-42-4-2-18(36)34-24-16(30)12-14(28)20(22(24)32)26(39)40/h11-12H,1-10H2,(H,33,35)(H,34,36)(H,37,38)(H,39,40)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6894722 | https://www.ncbi.nlm.nih.gov/pubmed/1242871 | https://www.ncbi.nlm.nih.gov/pubmed/182003

Iodoxamic acid (previously sold under the brand name Cholovue) is an organoiodine compound that was used as a contrast medium. It is intravenous cholecystocholangiographic agent. It features both a high iodine content as well as several hydrophilic groups.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Biliary tract diseases 11 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6894722 https://www.ncbi.nlm.nih.gov/pubmed/1242871 https://www.ncbi.nlm.nih.gov/pubmed/182003	Diagnostic		Approved 8429	CHOLOVUE Approved Use Contrast medium for biliary-tract radiography

Sourcing

Vendor/Aggregator	ID	URL
ABI Chem	AC1L1UBY
BOC Sciences	31127-82-9	https://www.bocsci.com/iodoxamic-acid-cas-31127-82-9-item-106766.html
ChemMol	99069281	http://www.chemmol.com/chemmol/99069281.html
Chemieliva Pharmaceutical Co., Ltd	PBCM1269562
NovoSeek	35740
PubChem	35740	https://pubchem.ncbi.nlm.nih.gov/compound/35740
Smolecule	S563848	https://www.smolecule.com/products/s563848

PubMed

Title	Date	PubMed
A new contrast medium for cholangio-cholecystography: meglumine iodoxamete.	1975 Sep	1242871
Double-blind comparison of meglumine lodoxamate (Cholovue) and meglumine iodipamide (Cholografin).	1976 Aug	182003
Intravenous cholangiography by bolus injection of meglumine iotroxamate and meglumine iodoxamate: a comparative trial of two new contrast media.	1981 Jul	6894722

Patents

Sample Use Guides

In Vivo Use Guide

A total of 90 patients were given an intravenous injection of 20 ml of 40% meglumine iodoxamate (iodoxamic acid) containing 183 mg/mI of organically bound iodine. The 20 ml dose was given intravenously over a 10 mm interval.

Route of Administration: Intravenous

In Vitro Use Guide

Unknown

Name

Type

Language

IODOXAMIC ACID

Official Name

English

ENDOMIRABIL

Brand Name

English

B-10610

Code

English

3,3'-(ETHYLENEBIS(OXYETHYLENEOXYETHYLENECARBONYLIMINO))BIS(2,4,6-TRIIODOBENZOIC ACID)

Systematic Name

English

iodoxamic acid [INN]

Common Name

English

ENDOBIL

Brand Name

English

IODOXAMIC ACID [USAN]

Common Name

English

B 10610

Code

English

IODOXAMIC ACID [II]

Common Name

English

SQ-21982

Code

English

VIDEOCOLANGIO

Brand Name

English

SQ 21982

Code

English

IODOXAMIC ACID [MART.]

Common Name

English

Iodoxamic acid [WHO-DD]

Common Name

English

IODOXAMIC ACID [JAN]

Common Name

English

BENZOIC ACID, 3,3'-((1,16-DIOXO-4,7,10,13-TETRAOXAHEXADECANE-1,16-DIYL)DIIMINO)BIS(2,4,6-TRIIODO-

Systematic Name

English

IODOXAMID

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28500