Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H20ClN3O.ClH |
| Molecular Weight | 366.285 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN(C)CCCN1C(=O)N(C2=C1C=CC(Cl)=C2)C3=CC=CC=C3
InChI
InChIKey=NQRQQRMSSZZIFE-UHFFFAOYSA-N
InChI=1S/C18H20ClN3O.ClH/c1-20(2)11-6-12-21-16-10-9-14(19)13-17(16)22(18(21)23)15-7-4-3-5-8-15;/h3-5,7-10,13H,6,11-12H2,1-2H3;1H
Clodazon (AW 142446) is an antidepressant drug investigated in Germany in the 1960s. In animal models, clodazon inhibits the catalepsy induced by tetrabenazine and it potentiates the effect of catecholamines, both effects being of the order experienced with imipramine. In clinical trials, about 2/3 of the patients showed a positive antidepressive effect with few side effects.
Approval Year
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NCI_THESAURUS |
C265
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admin on Mon Mar 31 18:50:39 GMT 2025 , Edited by admin on Mon Mar 31 18:50:39 GMT 2025
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300000055301
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N0FW29BP3C
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DTXSID70197698
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C78675
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4913-61-5
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56841979
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ACTIVE MOIETY
SUBSTANCE RECORD
