4-(Aminomethyl)benzoic acid hydrochloride

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H9NO2.ClH
Molecular Weight	187.623
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 4-(Aminomethyl)benzoic acid hydrochloride

SMILES

Cl.NCC1=CC=C(C=C1)C(O)=O

InChI

InChIKey=IQKLOQHWKQYTQZ-UHFFFAOYSA-N

InChI=1S/C8H9NO2.ClH/c9-5-6-1-3-7(4-2-6)8(10)11;/h1-4H,5,9H2,(H,10,11);1H

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Description

Aminomethylbenzoic acid (or p-aminomethylbenzoic acid, or PAMBA) an antifibrinolytic agent. This drug has been used for the treatment of internal hemorrhage during chronic disseminated intravascular coagulation.

Approval Year

PubMed

Show entries

Title	Date	PubMed
[Hematuria due to increased urokinase activity. Its successful treatment with p-aminomethylbenzoic acid (PAMBA)].	1965 Oct 8	5898922
[Clinical study on the efficacy of tranexamic acid in reducing postpartum blood lose: a randomized, comparative, multicenter trial].	2001 Oct	16134519
Synthesis and SAR of bis-statine based peptides as BACE 1 inhibitors.	2004 Jul 5	15177452
Selective n,n-dibenzylation of primary aliphatic amines with dibenzyl carbonate in the presence of phosphonium salts.	2004 May 28	15153031
Influence of a 4-aminomethylbenzoic acid residue on competitive fragmentation pathways during collision-induced dissociation of metal-cationized peptides.	2007	17902197

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Patents

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Name

Type

Language

4-(Aminomethyl)benzoic acid hydrochloride

Systematic Name

English

Benzoic acid, 4-(aminomethyl)-, hydrochloride (1:1)

Systematic Name

English

Benzoic acid, 4-(aminomethyl)-, hydrochloride

Common Name

English

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Code System

Code

Type

Description

EPA CompTox

DTXSID10217980

PRIMARY

PUBCHEM

105553

PRIMARY

CAS

67688-72-6

PRIMARY

ECHA (EC/EINECS)

266-903-9

PRIMARY

FDA UNII

MVW2TZW37D

PRIMARY

Showing 1 to 5 of 5 entries

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PARENT (SALT/SOLVATE)


					68WG9JKC7L

AMINOMETHYLBENZOIC ACID

SUBSTANCE RECORD


					MVW2TZW37D

4-(Aminomethyl)benzoic acid hydrochloride