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Details

Stereochemistry ACHIRAL
Molecular Formula C8H9NO2
Molecular Weight 151.1626
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMINOMETHYLBENZOIC ACID

SMILES

NCC1=CC=C(C=C1)C(O)=O

InChI

InChIKey=QCTBMLYLENLHLA-UHFFFAOYSA-N
InChI=1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11)

HIDE SMILES / InChI

Molecular Formula C8H9NO2
Molecular Weight 151.1626
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Aminomethylbenzoic acid (or p-aminomethylbenzoic acid, or PAMBA) an antifibrinolytic agent. This drug has been used for the treatment of internal hemorrhage during chronic disseminated intravascular coagulation.

Approval Year

PubMed

PubMed

TitleDatePubMed
Clinical pancreatology I: Pancreatic medical history.
2010-11
Choice of fluids for resuscitation in children with severe infection and shock: systematic review.
2010-09-02
Tanzanian farmers' knowledge and attitudes to GM biotechnology and the potential use of GM crops to provide improved levels of food security. A Qualitative Study.
2010-07-12
Tranexamic acid for preventing postpartum haemorrhage.
2010-07-07
Simultaneous determination of aminomethylbenzoic acid, cefminox sodium and etamsylate in human urine by capillary electrophoresis.
2010-07-01
Transport of the photodynamic therapy agent 5-aminolevulinic acid by distinct H+-coupled nutrient carriers coexpressed in the small intestine.
2010-01
Microbicides development programme: engaging the community in the standard of care debate in a vaginal microbicide trial in Mwanza, Tanzania.
2009-10-09
The role of transporters in the pharmacokinetics of orally administered drugs.
2009-09
Anti-fibrinolytic agents in post partum haemorrhage: a systematic review.
2009-07-15
New spectrophotometric and fluorimetric methods for determination of fluoxetine in pharmaceutical formulations.
2009
Simple spectrophotometric method for determination of paroxetine in tablets using 1,2-naphthoquinone-4-sulphonate as a chromogenic reagent.
2009
Incidence and clinical characteristics of group A rotavirus infections among children admitted to hospital in Kilifi, Kenya.
2008-07-22
The effect of intravesical instillation of antifibrinolytic agents on bacillus Calmette-Guerin treatment of superficial bladder cancer: A pilot study.
2008-07
The effect of intravesical instillation of antifibrinolytic agents on bacillus Calmette-Guerin treatment of superficial bladder cancer: a pilot study.
2008-04
Substituent effects on the energetics and aromaticity of aminomethylbenzoic acids.
2007-10-25
Study on enhancement of fibronectin-mediated bacillus Calmette-Guérin attachment to urinary bladder wall in rabbits.
2007-10
Cowpea bruchid Callosobruchus maculatus counteracts dietary protease inhibitors by modulating propeptides of major digestive enzymes.
2007-06
Spectrophotometric determination of aminomethylbenzoic acid using sodium 1,2-naphthoquinone-4-sulfonate as the chemical derivative chromogenic reagent.
2007-03
Radiosynthesis and evaluation of [11C]BTA-1 and [11C]3'-Me-BTA-1 as potential radiotracers for in vivo imaging of beta-amyloid plaques.
2007
Influence of a 4-aminomethylbenzoic acid residue on competitive fragmentation pathways during collision-induced dissociation of metal-cationized peptides.
2007
Severe malnutrition with and without HIV-1 infection in hospitalised children in Kampala, Uganda: differences in clinical features, haematological findings and CD4+ cell counts.
2006-10-16
Collision-induced dissociation of protonated tetrapeptides containing beta-alanine, gamma-aminobutyric acid, epsilon-aminocaproic acid or 4-aminomethylbenzoic acid residues.
2006
Effect of aromatic ring-containing drugs on carnitine biosynthesis in rats with special regard to p-aminomethylbenzoic acid.
2005-12
[Clinical investigation on the effect of intravesical instillation of antifibrinolytic agents with bacillus Calmette-Guerin on preventing bladder cancer recurrence].
2005-11-15
Novel fragmentation pathway for CID of (b(n) - 1 + Cat)+ ions from model, metal cationized peptides.
2005-08
Activation of vagal afferents in the rat duodenum by protein digests requires PepT1.
2005-06
Synthesis and SAR of bis-statine based peptides as BACE 1 inhibitors.
2004-07-05
Selective n,n-dibenzylation of primary aliphatic amines with dibenzyl carbonate in the presence of phosphonium salts.
2004-05-28
Flow-injection chemiluminescence determination of aminomethylbenzoic acid and aminophylline based on N-bromosuccinimide-luminol reaction.
2004-02-27
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis.
2003-02
The Cardiovascular Society in the GDR (German Democratic Republic).
2002
[Enhancement of bacillus Calmette-Guerin attachment to the bladder wall: experimental study].
2001-12
[Clinical study on the efficacy of tranexamic acid in reducing postpartum blood lose: a randomized, comparative, multicenter trial].
2001-10
[Hematuria due to increased urokinase activity. Its successful treatment with p-aminomethylbenzoic acid (PAMBA)].
1965-10-08
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:21:28 GMT 2025
Edited
by admin
on Mon Mar 31 19:21:28 GMT 2025
Record UNII
68WG9JKC7L
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMINOMETHYLBENZOIC ACID
MART.   WHO-DD  
Systematic Name English
TRANEXAMIC ACID RELATED COMPOUND D
USP  
Preferred Name English
NSC-41629
Code English
TRANEXAMIC ACID RELATED COMPOUND D [USP IMPURITY]
Common Name English
Aminomethylbenzoic acid [WHO-DD]
Common Name English
PAMBA
Common Name English
AMINOMETHYLBENZOIC ACID [MART.]
Common Name English
TRANEXAMIC ACID IMPURITY D [EP IMPURITY]
Common Name English
4-AMINOMETHYLBENZOIC ACID
Systematic Name English
Classification Tree Code System Code
WHO-VATC QB02AA03
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
WHO-ATC B02AA03
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
Code System Code Type Description
EVMPD
SUB12854MIG
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
WIKIPEDIA
AMINOMETHYLBENZOIC ACID
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
PUBCHEM
65526
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
ECHA (EC/EINECS)
200-297-9
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
ChEMBL
CHEMBL328875
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
FDA UNII
68WG9JKC7L
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
CAS
56-91-7
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
EPA CompTox
DTXSID20204568
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
DRUG CENTRAL
22
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
DRUG BANK
DB13244
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
NSC
41629
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
SMS_ID
100000077688
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY
RXCUI
14852
Created by admin on Mon Mar 31 19:21:28 GMT 2025 , Edited by admin on Mon Mar 31 19:21:28 GMT 2025
PRIMARY RxNorm
Related Record Type Details
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
Related Record Type Details
PARENT -> IMPURITY