4-(Aminomethyl)benzoic acid hydrochloride

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H9NO2.ClH
Molecular Weight	187.623
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 4-(Aminomethyl)benzoic acid hydrochloride

SMILES

Cl.NCC1=CC=C(C=C1)C(O)=O

InChI

InChIKey=IQKLOQHWKQYTQZ-UHFFFAOYSA-N

InChI=1S/C8H9NO2.ClH/c9-5-6-1-3-7(4-2-6)8(10)11;/h1-4H,5,9H2,(H,10,11);1H

HIDE SMILES / InChI

Molecular Formula	C8H9NO2
Molecular Weight	151.1626
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Aminomethylbenzoic acid (or p-aminomethylbenzoic acid, or PAMBA) an antifibrinolytic agent. This drug has been used for the treatment of internal hemorrhage during chronic disseminated intravascular coagulation.

Approval Year

PubMed

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Title	Date	PubMed
[Hematuria due to increased urokinase activity. Its successful treatment with p-aminomethylbenzoic acid (PAMBA)].	1965 Oct 8	5898922
[Enhancement of bacillus Calmette-Guerin attachment to the bladder wall: experimental study].	2001 Dec	16201181
[Clinical study on the efficacy of tranexamic acid in reducing postpartum blood lose: a randomized, comparative, multicenter trial].	2001 Oct	16134519
The Cardiovascular Society in the GDR (German Democratic Republic).	2002	12436747
Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis.	2003 Feb	12675525

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Patents

Substance Class	Chemical
Record UNII	MVW2TZW37D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

4-(Aminomethyl)benzoic acid hydrochloride

Systematic Name

English

Benzoic acid, 4-(aminomethyl)-, hydrochloride (1:1)

Systematic Name

English

Benzoic acid, 4-(aminomethyl)-, hydrochloride

Common Name

English

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Code System

Code

Type

Description

EPA CompTox

DTXSID10217980

PRIMARY

PUBCHEM

105553

PRIMARY

CAS

67688-72-6

PRIMARY

ECHA (EC/EINECS)

266-903-9

PRIMARY

FDA UNII

MVW2TZW37D

PRIMARY

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Related Record

Type

Details


					68WG9JKC7L

AMINOMETHYLBENZOIC ACID

PARENT -> SALT/SOLVATE

Amount:

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