MESUPRINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	MIXED
Molecular Formula	C19H26N2O5S
Molecular Weight	394.485
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MESUPRINE

Structure Search

SMILES

COC1=CC=C(CCNC(C)C(O)C2=CC=C(O)C(NS(C)(=O)=O)=C2)C=C1

InChI

InChIKey=REDZESHOHKCYCT-UHFFFAOYSA-N

InChI=1S/C19H26N2O5S/c1-13(20-11-10-14-4-7-16(26-2)8-5-14)19(23)15-6-9-18(22)17(12-15)21-27(3,24)25/h4-9,12-13,19-23H,10-11H2,1-3H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5538923 | https://www.ncbi.nlm.nih.gov/pubmed/4398626 | https://www.ncbi.nlm.nih.gov/pubmed/22185153 | https://link.springer.com/book/10.1007/978-1-4757-2085-3#about

Mesuprine is a β-adrenergic-receptor mimetic agent. It is a smooth muscle relaxant that prevents uterine contractility and premature labor.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Sulfonanilides. II. Analogs of Catecholamines.	1967 May 1	22185153
Inhibition of human premature labor by mesuprine hydrochloride.	1971 Jan	5538923
Effect of mesuprine hydrochloride upon nonpregnant uterine contractility and the cardiovascular system.	1971 Sep 15	4398626
Mesovarial leiomyomas in rats in a chronic toxicity study of mesuprine hydrochloride.	1972 Dec	4405031
The effect of mesuprine HC1 on selected smooth muscles.	1972 Mar	4154490

Patents

Patents

Name

Type

Language

MESUPRINE

Official Name

English

mesuprine [INN]

Common Name

English

METHANESULFONAMIDE, N-(2-HYDROXY-5-(1-HYDROXY-2-((2-(4-METHOXYPHENYL)ETHYL)AMINO)PROPYL)PHENYL)-

Systematic Name

English

Code System Code Type Description

SMS_ID

100000081190

Created by admin on Fri Dec 15 15:16:56 UTC 2023 , Edited by admin on Fri Dec 15 15:16:56 UTC 2023

PRIMARY

EPA CompTox

DTXSID60864089

Created by admin on Fri Dec 15 15:16:56 UTC 2023 , Edited by admin on Fri Dec 15 15:16:56 UTC 2023

PRIMARY

NCI_THESAURUS

C174707

Created by admin on Fri Dec 15 15:16:56 UTC 2023 , Edited by admin on Fri Dec 15 15:16:56 UTC 2023

PRIMARY

EVMPD

SUB08796MIG

Created by admin on Fri Dec 15 15:16:56 UTC 2023 , Edited by admin on Fri Dec 15 15:16:56 UTC 2023

PRIMARY

CAS

7541-30-2

Created by admin on Fri Dec 15 15:16:56 UTC 2023 , Edited by admin on Fri Dec 15 15:16:56 UTC 2023

PRIMARY

ChEMBL

CHEMBL2111039

Created by admin on Fri Dec 15 15:16:56 UTC 2023 , Edited by admin on Fri Dec 15 15:16:56 UTC 2023

PRIMARY

PUBCHEM

24171

Created by admin on Fri Dec 15 15:16:56 UTC 2023 , Edited by admin on Fri Dec 15 15:16:56 UTC 2023

PRIMARY

INN

2629

Created by admin on Fri Dec 15 15:16:56 UTC 2023 , Edited by admin on Fri Dec 15 15:16:56 UTC 2023

PRIMARY

FDA UNII

MEO9P8EX05

Created by admin on Fri Dec 15 15:16:56 UTC 2023 , Edited by admin on Fri Dec 15 15:16:56 UTC 2023

PRIMARY

ACTIVE MOIETY


					MEO9P8EX05

MESUPRINE