MESUPRINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	MIXED
Molecular Formula	C19H26N2O5S
Molecular Weight	394.485
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MESUPRINE

Structure Search

SMILES

COC1=CC=C(CCNC(C)C(O)C2=CC(NS(C)(=O)=O)=C(O)C=C2)C=C1

InChI

InChIKey=REDZESHOHKCYCT-UHFFFAOYSA-N

InChI=1S/C19H26N2O5S/c1-13(20-11-10-14-4-7-16(26-2)8-5-14)19(23)15-6-9-18(22)17(12-15)21-27(3,24)25/h4-9,12-13,19-23H,10-11H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C19H26N2O5S
Molecular Weight	394.485
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5538923 | https://www.ncbi.nlm.nih.gov/pubmed/4398626 | https://www.ncbi.nlm.nih.gov/pubmed/22185153 | https://link.springer.com/book/10.1007/978-1-4757-2085-3#about

Mesuprine is a β-adrenergic-receptor mimetic agent. It is a smooth muscle relaxant that prevents uterine contractility and premature labor.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Mesovarial leiomyomas in rats in a chronic toxicity study of mesuprine hydrochloride.	1972-12	4405031
The effect of mesuprine HC1 on selected smooth muscles.	1972-03	4154490
Effect of mesuprine hydrochloride upon nonpregnant uterine contractility and the cardiovascular system.	1971-09-15	4398626
Inhibition of human premature labor by mesuprine hydrochloride.	1971-01	5538923
Sulfonanilides. II. Analogs of Catecholamines.	1967-05-01	22185153

Patents

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:52:47 GMT 2025` Edited by `admin` on `Mon Mar 31 17:52:47 GMT 2025`
Record UNII	MEO9P8EX05
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MESUPRINE

Official Name

English

mesuprine [INN]

Preferred Name

English

METHANESULFONAMIDE, N-(2-HYDROXY-5-(1-HYDROXY-2-((2-(4-METHOXYPHENYL)ETHYL)AMINO)PROPYL)PHENYL)-

Systematic Name

English

Code System Code Type Description

SMS_ID

100000081190

Created by admin on Mon Mar 31 17:52:47 GMT 2025 , Edited by admin on Mon Mar 31 17:52:47 GMT 2025

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EPA CompTox

DTXSID60864089

Created by admin on Mon Mar 31 17:52:47 GMT 2025 , Edited by admin on Mon Mar 31 17:52:47 GMT 2025

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NCI_THESAURUS

C174707

Created by admin on Mon Mar 31 17:52:47 GMT 2025 , Edited by admin on Mon Mar 31 17:52:47 GMT 2025

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EVMPD

SUB08796MIG

Created by admin on Mon Mar 31 17:52:47 GMT 2025 , Edited by admin on Mon Mar 31 17:52:47 GMT 2025

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CAS

7541-30-2

Created by admin on Mon Mar 31 17:52:47 GMT 2025 , Edited by admin on Mon Mar 31 17:52:47 GMT 2025

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ChEMBL

CHEMBL2111039

Created by admin on Mon Mar 31 17:52:47 GMT 2025 , Edited by admin on Mon Mar 31 17:52:47 GMT 2025

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PUBCHEM

24171

Created by admin on Mon Mar 31 17:52:47 GMT 2025 , Edited by admin on Mon Mar 31 17:52:47 GMT 2025

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INN

2629

Created by admin on Mon Mar 31 17:52:47 GMT 2025 , Edited by admin on Mon Mar 31 17:52:47 GMT 2025

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FDA UNII

MEO9P8EX05

Created by admin on Mon Mar 31 17:52:47 GMT 2025 , Edited by admin on Mon Mar 31 17:52:47 GMT 2025

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Related Record Type Details


					MEO9P8EX05

MESUPRINE

ACTIVE MOIETY