PRENALTEROL

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C12H19NO3
Molecular Weight	225.2842
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PRENALTEROL

Structure Search

SMILES

CC(C)NC[C@H](O)COC1=CC=C(O)C=C1

InChI

InChIKey=ADUKCCWBEDSMEB-NSHDSACASA-N

InChI=1S/C12H19NO3/c1-9(2)13-7-11(15)8-16-12-5-3-10(14)4-6-12/h3-6,9,11,13-15H,7-8H2,1-2H3/t11-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7270401 | https://www.ncbi.nlm.nih.gov/pubmed/3191661 | https://www.ncbi.nlm.nih.gov/pubmed/2572262

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Beta-1 adrenergic receptor 158 Target ID: CHEMBL213 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1687080\|https://www.ncbi.nlm.nih.gov/pubmed/6131123\|https://www.ncbi.nlm.nih.gov/pubmed/6120845\|https://www.ncbi.nlm.nih.gov/pubmed/2564629	Partial Agonist 290		280.0 nM [Ki]

PubMed

PubMed

Title	Date	PubMed
Role of selective alpha and beta adrenergic receptor mechanisms in rat jejunal longitudinal muscle contractility.	2008 Jun	17879122
Towards a thermodynamic definition of efficacy in partial agonism: The thermodynamics of efficacy and ligand proton transfer in a G protein-coupled receptor of the rhodopsin class.	2010 Nov 15	20727346

Patents

Patents

Sample Use Guides

In Vivo Use Guide

The eight patients were given prenalterol (PNL) orally, 30 to 200 mg/day, versus placebo for 6 days

Route of Administration: Oral

Name

Type

Language

PRENALTEROL

Official Name

English

prenalterol [INN]

Common Name

English

Prenalterol [WHO-DD]

Common Name

English

(-)-(S)-1-(P-HYDROXYPHENOXY)-3-(ISOPROPYLAMINO)-2-PROPANOL

Common Name

English

PRENALTEROL [MI]

Common Name

English

PHENOL, 4-(2-HYDROXY-3-((1-METHYLETHYL)AMINO)PROPOXY)-

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QC01CA13

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

WHO-ATC

C01CA13

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

Code System Code Type Description

INN

4121

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

PRIMARY

MESH

D011294

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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FDA UNII

M4G34404CX

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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SMS_ID

100000081428

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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PUBCHEM

42396

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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DRUG BANK

DB13777

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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NCI_THESAURUS

C174691

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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EPA CompTox

DTXSID8023507

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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ECHA (EC/EINECS)

260-791-5

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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WIKIPEDIA

Prenalterol

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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EVMPD

SUB10027MIG

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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CAS

57526-81-5

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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DRUG CENTRAL

2258

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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ChEMBL

CHEMBL1160714

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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MERCK INDEX

m9123

Created by admin on Fri Dec 15 17:59:01 GMT 2023 , Edited by admin on Fri Dec 15 17:59:01 GMT 2023

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Merck Index

ACTIVE MOIETY


					M4G34404CX

SALT/SOLVATE (PARENT)


					U6VH18LCQ8

PRENALTEROL HYDROCHLORIDE