U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C2H6N2O
Molecular Weight 74.0818
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-NITROSODIMETHYLAMINE

SMILES

CN(C)N=O

InChI

InChIKey=UMFJAHHVKNCGLG-UHFFFAOYSA-N
InChI=1S/C2H6N2O/c1-4(2)3-5/h1-2H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Protection against drug- and chemical-induced multiorgan toxicity by a novel IH636 grape seed proanthocyanidin extract.
2001
Chromosome analysis of human spermatozoa following in vitro exposure to cyclophosphamide, benzo(a)pyrene and N-nitrosodimethylamine in the presence of rat liver S9.
2001 Apr 5
Attempt to adsorb N-nitrosamines in solution by use of zeolites.
2001 Aug
Ethanol enhances the formation of endogenously and exogenously derived adducts in rat hepatic DNA.
2001 Aug 8
Release of nitric oxide together with carbon-centered radicals from N-nitrosamines by ultraviolet light irradiation.
2001 Dec
Carbon tetrachloride changes the activity of cytochrome P450 system in the liver of male rats: role of antioxidants.
2001 Dec 14
Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis.
2001 Feb
Investigation of the enhancement of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis by 6-phenylhexyl isothiocyanate.
2001 Jan 10
[Changes of lipid peroxidation in liver fibrogenesis induced by dimethylnitrosamine and drugs' intervention].
2001 Jul
Determination of N-nitrosodimethylamine in artificial gastric juice by gas chromatography-mass spectrometry and by gas chromatography-thermal energy analysis.
2001 Jun
Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies.
2001 Jun 2
Carcinogenicity assays of wood dust and wood additives in rats exposed by long-term inhalation.
2001 Mar
Effect of cadmium and zinc-metallothionein on methemoglobin and nitric oxide in dimethylnitrosamine treated rats.
2001 May
Effects of octreotide on intestinal transit and bacterial translocation in conscious rats with portal hypertension and liver fibrosis.
2001 Nov
Induction of cytochrome P450-dependent monooxygenase in mouse liver and kidney by rutaecarpine, an alkaloid of the herbal drug Evodia rutaecarpa.
2001 Nov 30
TAC-101, a novel retinobenzoic-acid derivative, enhances gap junctional intercellular communication among renal epithelial cells treated with renal carcinogens.
2001 Nov-Dec
Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic.
2001 Oct
A kinetic model of N-nitrosodimethylamine (NDMA) formation during water chlorination/chloramination.
2002
Mechanistic studies of N-nitrosodimethylamine (NDMA) formation in chlorinated drinking water.
2002 Apr
Inhibitory effect of whole strawberries, garlic juice or kale juice on endogenous formation of N-nitrosodimethylamine in humans.
2002 Aug 8
Susceptibility of liver proliferative lesions in heterozygous p53 deficient CBA mice to various carcinogens.
2002 Jul
Effects of Wu-chu-yu-tang and its component herbs on drug-metabolizing enzymes.
2002 Jul
Impairment of activation of hepatocyte growth factor precursor into its mature form in rats with liver cirrhosis.
2002 Jul
Volatile N-nitrosamine inhibition after intake Korean green tea and Maesil (Prunus mume SIEB. et ZACC.) extracts with an amine-rich diet in subjects ingesting nitrate.
2002 Jul
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro.
2002 Jun
Pathogenic roles of tumor necrosis factor receptor p55-mediated signals in dimethylnitrosamine-induced murine liver fibrosis.
2002 May
Effect of some hypoglycemic herbs on the activity of phase I and II drug-metabolizing enzymes in alloxan-induced diabetic rats.
2002 May 24
Cytochrome P450 2E1 dependent catalytic activity and lipid peroxidation in rat blood lymphocytes.
2002 Oct 11
Monitoring of nitrite and N-nitrosamine levels in irradiated pork sausage.
2002 Sep
Patents

Patents

Name Type Language
N-NITROSODIMETHYLAMINE
HSDB   MI  
Systematic Name English
DIMETHYLNITROSAMINE
Common Name English
N-NITROSODIMETHYLAMINE [HSDB]
Common Name English
N-NITROSODIMETHYLAMINE [USP-RS]
Common Name English
DMN
Common Name English
N-NITROSODIMETHYLAMINE [IARC]
Common Name English
NDMA
Common Name English
DMNA
Common Name English
METHANAMINE, N-METHYL-N-NITROSO-
Systematic Name English
NSC-23226
Code English
NMDA (GENOTOXIC)
Common Name English
N-NITROSODIMETHYLAMINE [MI]
Common Name English
N-METHYL-N-NITROSOMETHANAMINE
Systematic Name English
Classification Tree Code System Code
IARC <i>N</i>-Nitrosodimethylamine
NCI_THESAURUS C45398
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
Code System Code Type Description
MERCK INDEX
m7994
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY Merck Index
CHEBI
59990
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
WIKIPEDIA
N-NITROSODIMETHYLAMINE
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
RS_ITEM_NUM
1466674
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
HSDB
1667
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
EPA CompTox
DTXSID7021029
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
MESH
D004128
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
PUBCHEM
6124
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
FDA UNII
M43H21IO8R
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
CHEBI
35807
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
ECHA (EC/EINECS)
200-549-8
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
NSC
23226
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
SMS_ID
100000183957
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
NCI_THESAURUS
C44417
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY
CAS
62-75-9
Created by admin on Fri Dec 15 15:01:38 GMT 2023 , Edited by admin on Fri Dec 15 15:01:38 GMT 2023
PRIMARY