Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C23H28N3O |
| Molecular Weight | 362.4879 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 1 |
SHOW SMILES / InChI
SMILES
CCN(CC)CC[N+]1=CC2=C(C)C3=C(NC4=C3C=C(O)C=C4)C(C)=C2C=C1
InChI
InChIKey=NGOHTJBYABHJKF-UHFFFAOYSA-O
InChI=1S/C23H27N3O/c1-5-25(6-2)11-12-26-10-9-18-16(4)23-22(15(3)20(18)14-26)19-13-17(27)7-8-21(19)24-23/h7-10,13-14,27H,5-6,11-12H2,1-4H3/p+1
Datelliptium is a DNA-intercalating agent, an analog of a natural alkaloid ellipticine. The compound was active in vivo against a variety of murine solid tumors. In a phase I clinical trial no objective complete or partial responses were observed in patients with solid tumors or lymphoma treated with datelliptium.
Approval Year
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C582
Created by
admin on Mon Mar 31 17:58:54 GMT 2025 , Edited by admin on Mon Mar 31 17:58:54 GMT 2025
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
L374Y6WE0D
Created by
admin on Mon Mar 31 17:58:54 GMT 2025 , Edited by admin on Mon Mar 31 17:58:54 GMT 2025
|
PRIMARY | |||
|
81531-57-9
Created by
admin on Mon Mar 31 17:58:54 GMT 2025 , Edited by admin on Mon Mar 31 17:58:54 GMT 2025
|
PRIMARY | |||
|
C83649
Created by
admin on Mon Mar 31 17:58:54 GMT 2025 , Edited by admin on Mon Mar 31 17:58:54 GMT 2025
|
PRIMARY | |||
|
72035
Created by
admin on Mon Mar 31 17:58:54 GMT 2025 , Edited by admin on Mon Mar 31 17:58:54 GMT 2025
|
PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
