U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C16H19NO2
Molecular Weight 257.3276
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEDIFOXAMINE

SMILES

CN(C)CC(OC1=CC=CC=C1)OC2=CC=CC=C2

InChI

InChIKey=QNMGHBMGNRQPNL-UHFFFAOYSA-N
InChI=1S/C16H19NO2/c1-17(2)13-16(18-14-9-5-3-6-10-14)19-15-11-7-4-8-12-15/h3-12,16H,13H2,1-2H3

HIDE SMILES / InChI
Medifoxamine, an antidepressive drug, preferentially inhibits dopamine reuptake. It was marketed in France, but because of the hepatotoxicity, then was withdrawn.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Hepatic tolerance of atypical antipsychotic drugs].
2002 Nov-Dec

Sample Use Guides

After an overnight fast, ascending doses of 200, 500, 750 and 1000 mg of medifoxamine were taken orally
Route of Administration: Oral
Name Type Language
MEDIFOXAMINE
INN   MART.   MI   WHO-DD  
INN  
Official Name English
medifoxamine [INN]
Common Name English
Medifoxamine [WHO-DD]
Common Name English
MEDIFOXAMINE [MI]
Common Name English
MEDIFOXAMINE [MART.]
Common Name English
(DIMETHYLAMINO)ACETALDEHYDE DIPHENYL ACETAL
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C66884
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
NCI_THESAURUS C47794
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
WHO-VATC QN06AX13
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
WHO-ATC N06AX13
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
Code System Code Type Description
WIKIPEDIA
MEDIFOXAMINE
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
PUBCHEM
36109
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
SMS_ID
100000081990
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
RXCUI
29434
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY RxNorm
MERCK INDEX
m7131
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY Merck Index
DRUG CENTRAL
1656
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
ChEMBL
CHEMBL85231
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
FDA UNII
KWU7C2A1NT
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
MESH
C034065
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
ECHA (EC/EINECS)
251-011-4
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
CAS
32359-34-5
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
INN
3759
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
EPA CompTox
DTXSID80186078
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
DRUG BANK
DB13219
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
NCI_THESAURUS
C83914
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY
EVMPD
SUB08693MIG
Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023
PRIMARY