MEDIFOXAMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H19NO2
Molecular Weight	257.3276
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MEDIFOXAMINE

Structure Search

SMILES

CN(C)CC(OC1=CC=CC=C1)OC2=CC=CC=C2

InChI

InChIKey=QNMGHBMGNRQPNL-UHFFFAOYSA-N

InChI=1S/C16H19NO2/c1-17(2)13-16(18-14-9-5-3-6-10-14)19-15-11-7-4-8-12-15/h3-12,16H,13H2,1-2H3

HIDE SMILES / InChI

Description
Sources: | https://www.ncbi.nlm.nih.gov/pubmed/12506267 | https://www.ncbi.nlm.nih.gov/pubmed/7114665

Medifoxamine, an antidepressive drug, preferentially inhibits dopamine reuptake. It was marketed in France, but because of the hepatotoxicity, then was withdrawn.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Hepatic tolerance of atypical antipsychotic drugs].	2002 Nov-Dec	12506267

Sample Use Guides

In Vivo Use Guide

After an overnight fast, ascending doses of 200, 500, 750 and 1000 mg of medifoxamine were taken orally

Route of Administration: Oral

Name

Type

Language

MEDIFOXAMINE

Official Name

English

medifoxamine [INN]

Common Name

English

Medifoxamine [WHO-DD]

Common Name

English

MEDIFOXAMINE [MI]

Common Name

English

MEDIFOXAMINE [MART.]

Common Name

English

(DIMETHYLAMINO)ACETALDEHYDE DIPHENYL ACETAL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66884

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

NCI_THESAURUS

C47794

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

WHO-VATC

QN06AX13

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

WHO-ATC

N06AX13

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

Code System Code Type Description

WIKIPEDIA

MEDIFOXAMINE

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

PUBCHEM

36109

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

SMS_ID

100000081990

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

RXCUI

29434

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

RxNorm

MERCK INDEX

m7131

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

Merck Index

DRUG CENTRAL

1656

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

ChEMBL

CHEMBL85231

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

FDA UNII

KWU7C2A1NT

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

MESH

C034065

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

ECHA (EC/EINECS)

251-011-4

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

CAS

32359-34-5

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

INN

3759

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

EPA CompTox

DTXSID80186078

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

DRUG BANK

DB13219

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

NCI_THESAURUS

C83914

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

EVMPD

SUB08693MIG

Created by admin on Fri Dec 15 16:47:22 GMT 2023 , Edited by admin on Fri Dec 15 16:47:22 GMT 2023

PRIMARY

ACTIVE MOIETY


					KWU7C2A1NT

SALT/SOLVATE (PARENT)


					OAG6T7TVU2

MEDIFOXAMINE FUMARATE