Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C26H46N2 |
Molecular Weight | 386.6568 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 6 / 6 |
E/Z Centers | 0 |
Charge | 2 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC=C3C[C@H](CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CCC[N+]4(C)C)[N+]5(C)CCCC5
InChI
InChIKey=JSIHCKINONIDNP-BEQZQCNLSA-N
InChI=1S/C26H46N2/c1-25-14-12-21(28(5)17-6-7-18-28)19-20(25)10-11-22-23(25)13-15-26(2)24(22)9-8-16-27(26,3)4/h10,21-24H,6-9,11-19H2,1-5H3/q+2/t21-,22+,23-,24-,25-,26-/m0/s1
Candocuronium is bisquaternary aza steroid derivative with neuromuscular blocking, ganglion blocking, and vagolytic activities. Its potential adjunctive use in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation was briefly evaluated in clinical studies in India, but further development discontinued because of attendant cardiovascular effects, primarily tachycardia that was no worse than but also not an improvement over the clinically established pancuronium bromide.
Originator
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2151453
0.2 and 0.25 mg/kg
Route of Administration:
Intravenous
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NCI_THESAURUS |
C66886
Created by
admin on Fri Dec 15 17:08:47 GMT 2023 , Edited by admin on Fri Dec 15 17:08:47 GMT 2023
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C87310
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736874-16-1
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DTXSID80223957
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Candocuronium
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71538
Created by
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IQ9FO41C89
Created by
admin on Fri Dec 15 17:08:47 GMT 2023 , Edited by admin on Fri Dec 15 17:08:47 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)