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Details

Stereochemistry ABSOLUTE
Molecular Formula C26H46N2
Molecular Weight 386.6568
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 8
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of CANDOCURONIUM

SMILES

C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CCC[N+]4(C)C)[N+]5(C)CCCC5

InChI

InChIKey=JSIHCKINONIDNP-BEQZQCNLSA-N
InChI=1S/C26H46N2/c1-25-14-12-21(28(5)17-6-7-18-28)19-20(25)10-11-22-23(25)13-15-26(2)24(22)9-8-16-27(26,3)4/h10,21-24H,6-9,11-19H2,1-5H3/q+2/t21-,22+,23-,24-,25-,26-/m0/s1

HIDE SMILES / InChI

Molecular Formula C26H46N2
Molecular Weight 386.6568
Charge 2
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 6 / 8
E/Z Centers 0
Optical Activity UNSPECIFIED

Candocuronium is bisquaternary aza steroid derivative with neuromuscular blocking, ganglion blocking, and vagolytic activities. Its potential adjunctive use in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation was briefly evaluated in clinical studies in India, but further development discontinued because of attendant cardiovascular effects, primarily tachycardia that was no worse than but also not an improvement over the clinically established pancuronium bromide.

Approval Year

PubMed

PubMed

TitleDatePubMed
Neuromuscular and other blocking actions of a new series of mono and bisquaternary aza steroids.
1974-11

Sample Use Guides

0.2 and 0.25 mg/kg
Route of Administration: Intravenous
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:40:48 GMT 2025
Edited
by admin
on Mon Mar 31 18:40:48 GMT 2025
Record UNII
IQ9FO41C89
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
17A,17A-DIMETHYL-3.BETA.-(1-METHYLPYRROLIDINIO)-17A-AZONIA-D-HOMOANDROST-5-ENE
Preferred Name English
CANDOCURONIUM
Common Name English
CANDOCURONIUM CATION
Common Name English
CANDOCURONIUM ION
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C66886
Created by admin on Mon Mar 31 18:40:48 GMT 2025 , Edited by admin on Mon Mar 31 18:40:48 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C87310
Created by admin on Mon Mar 31 18:40:48 GMT 2025 , Edited by admin on Mon Mar 31 18:40:48 GMT 2025
PRIMARY
CAS
736874-16-1
Created by admin on Mon Mar 31 18:40:48 GMT 2025 , Edited by admin on Mon Mar 31 18:40:48 GMT 2025
PRIMARY
EPA CompTox
DTXSID80223957
Created by admin on Mon Mar 31 18:40:48 GMT 2025 , Edited by admin on Mon Mar 31 18:40:48 GMT 2025
PRIMARY
WIKIPEDIA
Candocuronium
Created by admin on Mon Mar 31 18:40:48 GMT 2025 , Edited by admin on Mon Mar 31 18:40:48 GMT 2025
PRIMARY
PUBCHEM
71538
Created by admin on Mon Mar 31 18:40:48 GMT 2025 , Edited by admin on Mon Mar 31 18:40:48 GMT 2025
PRIMARY
FDA UNII
IQ9FO41C89
Created by admin on Mon Mar 31 18:40:48 GMT 2025 , Edited by admin on Mon Mar 31 18:40:48 GMT 2025
PRIMARY
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SALT/SOLVATE -> PARENT
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