Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C26H46N2.2I |
Molecular Weight | 640.4658 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 6 / 6 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[I-].[I-].[H][C@@]12CC=C3C[C@H](CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CCC[N+]4(C)C)[N+]5(C)CCCC5
InChI
InChIKey=GGAGIPMNQXAXNH-XDMKMBKMSA-L
InChI=1S/C26H46N2.2HI/c1-25-14-12-21(28(5)17-6-7-18-28)19-20(25)10-11-22-23(25)13-15-26(2)24(22)9-8-16-27(26,3)4;;/h10,21-24H,6-9,11-19H2,1-5H3;2*1H/q+2;;/p-2/t21-,22+,23-,24-,25-,26-;;/m0../s1
Molecular Formula | HI |
Molecular Weight | 127.9124 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C26H46N2 |
Molecular Weight | 386.6568 |
Charge | 2 |
Count |
|
Stereochemistry | MIXED |
Additional Stereochemistry | No |
Defined Stereocenters | 6 / 6 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Candocuronium is bisquaternary aza steroid derivative with neuromuscular blocking, ganglion blocking, and vagolytic activities. Its potential adjunctive use in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation was briefly evaluated in clinical studies in India, but further development discontinued because of attendant cardiovascular effects, primarily tachycardia that was no worse than but also not an improvement over the clinically established pancuronium bromide.
Originator
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2151453
0.2 and 0.25 mg/kg
Route of Administration:
Intravenous
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:33:13 GMT 2023
by
admin
on
Fri Dec 15 16:33:13 GMT 2023
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Record UNII |
SC80GNP08C
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Record Status |
Validated (UNII)
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Record Version |
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-
Download
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C66886
Created by
admin on Fri Dec 15 16:33:13 GMT 2023 , Edited by admin on Fri Dec 15 16:33:13 GMT 2023
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Code System | Code | Type | Description | ||
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SUB06071MIG
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71537
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CHEMBL2110803
Created by
admin on Fri Dec 15 16:33:13 GMT 2023 , Edited by admin on Fri Dec 15 16:33:13 GMT 2023
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C77364
Created by
admin on Fri Dec 15 16:33:13 GMT 2023 , Edited by admin on Fri Dec 15 16:33:13 GMT 2023
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SC80GNP08C
Created by
admin on Fri Dec 15 16:33:13 GMT 2023 , Edited by admin on Fri Dec 15 16:33:13 GMT 2023
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PRIMARY | |||
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54278-85-2
Created by
admin on Fri Dec 15 16:33:13 GMT 2023 , Edited by admin on Fri Dec 15 16:33:13 GMT 2023
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7119
Created by
admin on Fri Dec 15 16:33:13 GMT 2023 , Edited by admin on Fri Dec 15 16:33:13 GMT 2023
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100000081601
Created by
admin on Fri Dec 15 16:33:13 GMT 2023 , Edited by admin on Fri Dec 15 16:33:13 GMT 2023
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CANDOCURONIUM IODIDE
Created by
admin on Fri Dec 15 16:33:13 GMT 2023 , Edited by admin on Fri Dec 15 16:33:13 GMT 2023
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DTXSID60969306
Created by
admin on Fri Dec 15 16:33:13 GMT 2023 , Edited by admin on Fri Dec 15 16:33:13 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
Related Record | Type | Details | ||
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ACTIVE MOIETY |