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Details

Stereochemistry RACEMIC
Molecular Formula C27H31ClN2O.2ClH
Molecular Weight 507.923
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHLORBENZOXAMINE HYDROCHLORIDE

SMILES

Cl.Cl.CC1=CC=CC=C1CN2CCN(CCOC(C3=CC=CC=C3)C4=CC=CC=C4Cl)CC2

InChI

InChIKey=ZTACEXAAXMFRGD-UHFFFAOYSA-N
InChI=1S/C27H31ClN2O.2ClH/c1-22-9-5-6-12-24(22)21-30-17-15-29(16-18-30)19-20-31-27(23-10-3-2-4-11-23)25-13-7-8-14-26(25)28;;/h2-14,27H,15-21H2,1H3;2*1H

HIDE SMILES / InChI
Chlorbenzoxamine is an antimuscarinic agent used for the treatment of peptic ulcer disease and other functional gastrointestinal disorders. Chlorbenzoxamine, a structural analog of hydroxyzine, produces a unique antagonism of gastric ulceration induced in rats and dogs by various procedures. This effect is not accompanied by a significant gastric secretory depression or a reduction in gastric acid concentration. Chlorbenzoxamine does not show anticholinergic or antihistaminic activity in vitro but does produce a nonspecific depression of isolated smooth muscle. The antiulcer effect of chlorbenzoxamine in rats is abolished by hypophysectomy suggesting a central or endocrine mechanism of action.

Approval Year

PubMed

PubMed

TitleDatePubMed
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.
2010 Dec
Name Type Language
CHLORBENZOXAMINE HYDROCHLORIDE
MART.   WHO-DD  
Common Name English
CHLORBENZOXAMINE HYDROCHLORIDE [MART.]
Common Name English
CHLORBENZOXAMINE HCL
Common Name English
Chlorbenzoxamine hydrochloride [WHO-DD]
Common Name English
UCB-1474
Code English
CHLORBENZOXAMINE DIHYDROCHLORIDE
MI  
Common Name English
NSC-169098
Code English
UCB 1474
Code English
CHLORBENZOXAMINE DIHYDROCHLORIDE [MI]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29704
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
Code System Code Type Description
MERCK INDEX
m3351
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY Merck Index
EVMPD
SUB01210MIG
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY
ECHA (EC/EINECS)
226-951-3
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY
FDA UNII
I898I67K6S
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY
CAS
5576-62-5
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY
PUBCHEM
110673
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110781
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY
SMS_ID
100000084692
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY
NCI_THESAURUS
C78066
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY
NSC
169098
Created by admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
PRIMARY