Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C27H31ClN2O.2ClH |
| Molecular Weight | 507.923 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.CC1=CC=CC=C1CN2CCN(CCOC(C3=CC=CC=C3)C4=CC=CC=C4Cl)CC2
InChI
InChIKey=ZTACEXAAXMFRGD-UHFFFAOYSA-N
InChI=1S/C27H31ClN2O.2ClH/c1-22-9-5-6-12-24(22)21-30-17-15-29(16-18-30)19-20-31-27(23-10-3-2-4-11-23)25-13-7-8-14-26(25)28;;/h2-14,27H,15-21H2,1H3;2*1H
| Molecular Formula | C27H31ClN2O |
| Molecular Weight | 435.001 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Chlorbenzoxamine is an antimuscarinic agent used for the treatment of peptic ulcer disease and other functional gastrointestinal disorders. Chlorbenzoxamine, a structural analog of hydroxyzine, produces a unique antagonism of gastric ulceration induced in rats and dogs by various procedures. This effect is not accompanied by a significant gastric secretory depression or a reduction in gastric acid concentration. Chlorbenzoxamine does not show anticholinergic or antihistaminic activity in vitro but does produce a nonspecific depression of isolated smooth muscle. The antiulcer effect of chlorbenzoxamine in rats is abolished by hypophysectomy suggesting a central or endocrine mechanism of action.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:38:55 GMT 2023
by
admin
on
Fri Dec 15 16:38:55 GMT 2023
|
| Record UNII |
I898I67K6S
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Code | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C29704
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
m3351
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY | Merck Index | ||
|
SUB01210MIG
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY | |||
|
226-951-3
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY | |||
|
I898I67K6S
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY | |||
|
5576-62-5
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY | |||
|
110673
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY | |||
|
CHEMBL2110781
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY | |||
|
100000084692
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY | |||
|
C78066
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY | |||
|
169098
Created by
admin on Fri Dec 15 16:38:55 GMT 2023 , Edited by admin on Fri Dec 15 16:38:55 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |