Details
Stereochemistry | MIXED |
Molecular Formula | C26H56N10.2ClH |
Molecular Weight | 581.712 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 0 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC
InChI
InChIKey=BRJJFBHTDVWTCJ-UHFFFAOYSA-N
InChI=1S/C26H56N10.2ClH/c1-5-9-15-21(7-3)19-33-25(29)35-23(27)31-17-13-11-12-14-18-32-24(28)36-26(30)34-20-22(8-4)16-10-6-2;;/h21-22H,5-20H2,1-4H3,(H5,27,29,31,33,35)(H5,28,30,32,34,36);2*1H
Alexidine dihydrochloride, an antibacterial compound, which is used during endodontic procedures. It is a dibiguanide ahent and is effective inhibitor of protein tyrosine phosphatases localized to mitochondrion 1 (PTPMT1). It was noted that PTPMT1 could serve as a pharmacological target in the treatment of type II diabetes. Alexidine dihydrochloride is also an apoptosis-promoting agent possessing the anticancer properties.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL2052033 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20167843 |
1.08 µM [IC50] |
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I2A7616PY1
Created by
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102678
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DTXSID5045881
Created by
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1715-30-6
Created by
admin on Fri Dec 15 17:12:51 GMT 2023 , Edited by admin on Fri Dec 15 17:12:51 GMT 2023
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216-994-6
Created by
admin on Fri Dec 15 17:12:51 GMT 2023 , Edited by admin on Fri Dec 15 17:12:51 GMT 2023
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ACTIVE MOIETY
SUBSTANCE RECORD